CAS 1122-47-0

1-methylcytosine

Description:

1-Methylcytosine is a modified nucleobase derived from cytosine, one of the four primary bases in nucleic acids. It is characterized by the addition of a methyl group to the nitrogen atom at the 1-position of the cytosine ring. This modification plays a significant role in various biological processes, particularly in the regulation of gene expression and the maintenance of genomic stability. 1-Methylcytosine is often found in the context of DNA and RNA, influencing the structure and function of nucleic acids. Its presence can affect base pairing and the overall stability of nucleic acid structures. Additionally, this modification is associated with epigenetic mechanisms, where it can impact transcriptional activity without altering the underlying DNA sequence. The compound is of interest in research related to epigenetics, cancer biology, and developmental processes. Its CAS number, 1122-47-0, allows for precise identification in chemical databases and literature. Overall, 1-methylcytosine serves as an important biomolecule in understanding the complexities of genetic regulation and expression.

Formula: C₅H₇N₃O

InChI: InChI=1/C5H7N3O/c1-8-3-2-4(6)7-5(8)9/h2-3H,1H3,(H2,6,7,9)

InChI key: InChIKey=HWPZZUQOWRWFDB-UHFFFAOYSA-N

SMILES: O=C1N(C)C=CC(N)=N1

Synonyms:

• 2(1H)-Pyrimidinone, 4-amino-1-methyl-
• 4-Amino-1-methyl-2(1H)-pyrimidinone
• 4-amino-1-methylpyrimidin-2(1H)-one
• Cytosine, 1-methyl-
• N-Methylcytosine
• N¹-Methylcytosine
• Nsc 47693
• N1-Methylcytosine
• 1-Methylcytosine
• RARECHEM AQ NN 0292
• 4-amino-1-methyl-pyrimidin-2-one
• 4-azanyl-1-methyl-pyrimidin-2-one
• 1-METHYLCYTOSIN
• 4-AMino-1-Methyl-1H-pyriMidin-2-one
• 4-amino-1-methylpyrimidin-2-one
• 1-Methyl-4-aminopyrimidine-2(1H)-one
• 1-Methyl-1,2,3,4-tetrahydro-4-iminopyrimidine-2-one
• 1-Methyl-4-amino-1,2-dihydropyrimidine-2-one

4-Amino-1-methylpyrimidin-2(1H)-one

CAS: 1122-47-0

Formula: C₅H₇N₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.1286

Ref: IN-DA00833J

1-Methylcytosine

CAS: 1122-47-0

1-Methylcytosine

Purity: ≥98%

Molecular weight: 125.13g/mol

Ref: 54-BUP16409

1-Methylcytosine

CAS: 1122-47-0

1-Methylcytosine

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 125.13g/mol

Ref: 54-OR302541

4-Amino-1-methylpyrimidin-2(1H)-one

Controlled Product

CAS: 1122-47-0

Formula: C₅H₇N₃O

Color and Shape: Off White

Molecular weight: 125.12

Ref: TR-A898218

4-Amino-1-methylpyrimidin-2(1H)-one

CAS: 1122-47-0

Formula: C₅H₇N₃O

Purity: 97%

Color and Shape: Solid

Molecular weight: 125.131

Ref: 10-F462151

1-Methylcytosine

CAS: 1122-47-0

1-Methylcytosine (4-amino-1-methylpyrimidin-2(1H)-one) is a methylated form of the cytosine and can be used as the nucleobase of hachimoji DNA paired with

Formula: C₅H₇N₃O

Purity: 99.88%

Color and Shape: Solid

Molecular weight: 125.13

Ref: TM-T10019

4-Amino-1-methylpyrimidin-2(1H)-one

CAS: 1122-47-0

4-Amino-1-methylpyrimidin-2(1H)-one is a chemical compound that belongs to the group of pyrimidine compounds. It has been shown to be an inhibitor of viral life, with its activity against HIV being most well studied. The tautomers of 4-amino-1-methylpyrimidin-2(1H)-one are protonated and stable, meaning that they do not undergo any chemical change in the body. 4-Amino-1-methylpyrimidin-2(1H)-one is also able to form stable complexes with nitrogen atoms. The xray crystal structure for this compound shows that it coordinates with group P2, which contains two nitrogen atoms and one oxygen atom. The interaction between these three atoms is called a dinucleotide phosphate. This group binds to DNA by hydrogen bonds, forming intramolecular hydrogen bonds. The groups on the other side of the molecule bind

Formula: C₅H₇N₃O

Purity: Min. 95%

Molecular weight: 125.13 g/mol

Ref: 3D-BAA12247