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CAS 1122-58-3

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4-Dimethylaminopyridine

Description:
4-Dimethylaminopyridine (DMAP) is a versatile organic compound commonly used as a catalyst in various chemical reactions, particularly in acylation and esterification processes. It features a pyridine ring substituted with two dimethylamino groups at the 4-position, which enhances its nucleophilicity and makes it an effective catalyst for activating electrophiles. DMAP is a colorless to pale yellow solid at room temperature, with a characteristic amine-like odor. It is soluble in polar organic solvents such as acetone, ethanol, and dichloromethane, but has limited solubility in water. The compound exhibits basic properties due to the presence of the nitrogen atom in the pyridine ring, allowing it to participate in proton transfer reactions. DMAP is known for its ability to facilitate reactions under mild conditions, making it a valuable reagent in organic synthesis. However, it should be handled with care, as it can be toxic and irritating to the skin and respiratory system. Proper safety precautions, including the use of personal protective equipment, are recommended when working with this substance.
Formula:C7H10N2
InChI:InChI=1/C7H10N2/c1-9(2)7-3-5-8-6-4-7/h3-6H,1-2H3/p+1
InChI key:InChIKey=VHYFNPMBLIVWCW-UHFFFAOYSA-N
SMILES:N(C)(C)C=1C=CN=CC1
Synonyms:
  • 26Dclpy
  • 4 Dimethylamino Pyridine
  • 4-(Dimethylamino) PyridineForSynthesis
  • 4-(Dimethylamino)-Pyridin
  • 4-(Dimethylamino)Pyridine Solution
  • 4-(Dimethylamino)Pyridinium
  • 4-(Dimethylamino)pyridine, 99%, prilled
  • 4-(Dimethylamino)pyridine, ReagentPlus
  • 4-(N,N-Dimethylamino)pyridine
  • 4-Dimethyl amino pyridine
  • See more synonyms
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