CAS 112208-00-1

PALMITOYL-CYS((RS)-2,3-DI(PALMITOYLOXY)-PROPYL)-SER-LYS-LYS-LYS-LYS-OH

Description:

Palmitoyl-CYS((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Lys-Lys-Lys-Lys-OH, with CAS number 112208-00-1, is a synthetic peptide derivative characterized by its amphiphilic nature due to the presence of multiple palmitoyl groups. These fatty acid chains enhance its hydrophobic properties, facilitating membrane interaction and potential incorporation into lipid bilayers. The peptide sequence includes cysteine, serine, and multiple lysine residues, contributing to its structural stability and potential for forming disulfide bonds. The presence of lysine residues imparts a positive charge, which can influence its solubility and interaction with negatively charged biomolecules. This compound is often studied for its applications in drug delivery systems, particularly in enhancing cellular uptake and targeting specific tissues. Its unique structure allows for potential use in various biotechnological and pharmaceutical applications, including as a carrier for therapeutic agents. Overall, the combination of hydrophobic and hydrophilic characteristics makes it a versatile candidate for further research in the fields of biochemistry and molecular biology.

Formula: C₈₁H₁₅₆N₁₀O₁₃S

InChI: InChI=1/C81H156N10O13S/c1-4-7-10-13-16-19-22-25-28-31-34-37-40-55-73(93)86-72(65-105-64-66(104-75(95)57-42-39-36-33-30-27-24-21-18-15-12-9-6-3)63-103-74(94)56-41-38-35-32-29-26-23-20-17-14-11-8-5-2)80(100)91-71(62-92)79(99)89-68(52-44-48-59-83)77(97)87-67(51-43-47-58-82)76(96)88-69(53-45-49-60-84)78(98)90-70(81(101)102)54-46-50-61-85/h66-72,92H,4-65,82-85H2,1-3H3,(H,86,93)(H,87,97)(H,88,96)(H,89,99)(H,90,98)(H,91,100)(H,101,102)/t66?,67-,68-,69-,70-,71-,72-/m0/s1

SMILES: CCCCCCCCCCCCCCCC(=N[C@@H](CSCC(COC(=O)CCCCCCCCCCCCCCC)OC(=O)CCCCCCCCCCCCCCC)C(=N[C@@H](CO)C(=N[C@@H](CCCCN)C(=N[C@@H](CCCCN)C(=N[C@@H](CCCCN)C(=N[C@@H](CCCCN)C(=O)O)O)O)O)O)O)O

Synonyms:

• Pam3-Cys-Ser-Lys-Lys-Lys-Lys-Oh
• N-Palmitoyl-S-(2,3-Bis(Palmitoyloxy)Propyl)Cysteinyl-Seryl-Lysyl-Lysyl-Lysyl-Ly
• Sine
• N-palmitoyl-S-(2,3-bis(palmitoyloxy)propyl)cysteinyl-seryl-lysyl-lysyl-lysyl-lysine
• S-[2,3-bis(hexadecanoyloxy)propyl]-N-hexadecanoyl-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysine

S-[2,3-Bis[(1-oxohexadecyl)oxy]propyl]-N-(1-oxohexadecyl)-L-cysteinyl-L-seryl-L-lysyl-L-lysyl-L-lysyl-L-lysine

CAS: 112208-00-1

Formula: C₈₁H₁₅₆N₁₀O₁₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1510.2295

Ref: IN-DA008RDL

Pam3CSK4

CAS: 112208-00-1

Pam3CSK4 is a synthetic triacylated lipopeptide (LP) that mimics the acylated amino terminus of bacterial LPs.

Formula: C₈₁H₁₅₆N₁₀O₁₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 1510.23

Ref: TM-TP1068

Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Lys-Lys-Lys-Lys-OH trifluoroacetate salt

CAS: 112208-00-1

Agonist of toll-like receptors TLR1/2

Formula: C₈₁H₁₅₆N₁₀O₁₃S

Purity: Min. 95%

Molecular weight: 1,510.23 g/mol

Ref: 3D-FP109571

Palmitoyl-Cys((RS)-2,3-di(palmitoyloxy)-propyl)-Ser-Lys-Lys-Lys-Lys-OH

CAS: 112208-00-1

The non-toxic lipopeptide Pam3CSKKKK is a highly effective adjuvant for parenteral, oral and nasal immunizations. It readily dissolves in aqueous solvents and might also be applicable for DNA immunizations.

Formula: C₈₁H₁₅₆N₁₀O₁₃S

Purity: > 95%

Color and Shape: White Powder

Molecular weight: 1510.26

Ref: 01-4033506