CAS 112247-65-1

Biotin-[2-(2-pyridyldithio)ethylamide]

Description:

Biotin-[2-(2-pyridyldithio)ethylamide], with the CAS number 112247-65-1, is a biotin derivative that features a pyridyldithio moiety, which enhances its utility in biochemical applications, particularly in bioconjugation and labeling. This compound retains the essential properties of biotin, including its ability to bind specifically to avidin or streptavidin, making it valuable in various biochemical assays and techniques. The presence of the 2-(2-pyridyldithio)ethylamide group introduces a disulfide bond, which can be cleaved under reducing conditions, allowing for controlled release or modification of the biotin moiety. This characteristic is particularly useful in the development of targeted drug delivery systems and in the design of biosensors. The compound is typically soluble in polar organic solvents, and its stability can be influenced by environmental factors such as pH and temperature. Overall, Biotin-[2-(2-pyridyldithio)ethylamide] serves as a versatile tool in molecular biology and biochemistry, facilitating the study of protein interactions and cellular processes.

Formula: C₁₇H₂₄N₄O₂S₃

InChI: InChI=1/C17H24N4O2S3/c22-14(18-9-10-25-26-15-7-3-4-8-19-15)6-2-1-5-13-16-12(11-24-13)20-17(23)21-16/h3-4,7-8,12-13,16H,1-2,5-6,9-11H2,(H,18,22)(H2,20,21,23)/t12?,13-,16?/m0/s1

SMILES: C(CCC(=NCCSSc1ccccn1)O)C[C@H]1C2C(CS1)N=C(N2)O

Synonyms:

• N-[2-(2-Pyridyldithio)ethyl]biotinamide
• 5-[(3aS,4S,6aR)-2-Oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]-N-[2-(pyridin-2-yldisulphanyl)ethyl]pentanamide
• Biotin-[2-(pyridin-2-ylthio)ethylamide]
• [3aS-(3aα,4β,6aα)]-Hexahydro-2-oxo-N-[2-(2-pyridinyldithio)ethyl]-1H-thieno[3,4-d]iMidazole-4-pentanaMide

Biotin-[2-(2-pyridyldithio)ethylamide]

CAS: 112247-65-1

Formula: C₁₇H₂₄N₄O₂S₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 412.5931

Ref: IN-DA00833G

N-[2-(2-Pyridyldithio)ethyl]biotinamide

CAS: 112247-65-1

Formula: C₁₇H₂₄N₄O₂S₃

Purity: >97.0%(HPLC)

Color and Shape: White to Light yellow to Light orange powder to crystal

Molecular weight: 412.59

Ref: 3B-P2471

Biotin-[2-(pyridin-2-ylthio)ethylamide]

CAS: 112247-65-1

Biotin-[2-(pyridin-2-ylthio)ethylamide]

Formula: C₁₇H₂₄N₄O₂S₃

Purity: ≥95%

Color and Shape: off-white solid

Molecular weight: 412.59g/mol

Ref: 54-OR3150T

Biotin-[2-(2-pyridyldithio)ethylamide]

Controlled Product

CAS: 112247-65-1

Applications A sulfhydryl reactive biotinylaton reagent.
References Carlsson, J., et al.: Biochem. J., 173, 723 (1978), Ghebrehiwet, B., et al.: J. Immunol. Methods, 110, 251 (1988)

Formula: C₁₇H₂₄N₄O₂S₃

Color and Shape: White To Light Yellow

Molecular weight: 412.59

Ref: TR-B391500

(+)-Biotin-PDA

CAS: 112247-65-1

Please enquire for more information about (+)-Biotin-PDA including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₁₇H₂₄N₄S₃O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 412.6 g/mol

Ref: 3D-FB52758

Biotin-C2-S-S-pyridine

CAS: 112247-65-1

Biotin-C2-S-S-pyridine is a degradable ADC linker used for synthesizing antibody-drug conjugates (ADCs).

Formula: C₁₇H₂₄N₄O₂S₃

Color and Shape: Solid

Molecular weight: 412.59

Ref: TM-T89482