CAS 1123-54-2

7-amino-1H-triazolo[4,5-d]pyrimidine

Description:

7-Amino-1H-triazolo[4,5-d]pyrimidine is a heterocyclic compound characterized by its fused triazole and pyrimidine rings, which contribute to its unique chemical properties. This compound features an amino group at the 7-position of the triazole ring, enhancing its potential for hydrogen bonding and reactivity. It is typically a crystalline solid and exhibits moderate solubility in polar solvents, which is common for many nitrogen-containing heterocycles. The presence of multiple nitrogen atoms in its structure often imparts basicity, allowing it to participate in various chemical reactions, including nucleophilic substitutions and coordination with metal ions. This compound is of interest in medicinal chemistry due to its potential biological activities, including antimicrobial and antitumor properties. Additionally, its structural features make it a candidate for further modifications to enhance its pharmacological profile. Overall, 7-amino-1H-triazolo[4,5-d]pyrimidine is a versatile compound with significant implications in both synthetic and medicinal chemistry.

Formula: C₄H₄N₆

InChI: InChI=1/C4H4N6/c5-3-2-4(7-1-6-3)9-10-8-2/h1-2H,(H2,5,6,7,8,9)

InChI key: InChIKey=HRYKDUPGBWLLHO-UHFFFAOYSA-N

SMILES: NC1=C2C(=NC=N1)N=NN2

Synonyms:

• 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine
• 1H-v-Triazolo(4,5-d)pyrimidin-7-amine
• 1H-v-Triazolo(4,5-d)pyrimidine, 7-amino- (8CI)
• 1H-v-Triazolo[4,5-d]pyrimidine, 7-amino-
• 3H-1,2,3-Triazolo(4,5-d)pyrimidin-7-amine
• 3H-N-Triazolo(4,5-d)pyrimidin-7-amine
• 6-Amino-
• 6-Amino-8-azapurine
• 7-Amino-1-v-triazolo(d)pyrimidine
• 7-Amino-1H-v-triazolo(4,5-d)pyrimidine
• 7-Amino-v-triazolo(d)pyrimidine
• 7aH-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine
• 8-Aza-6-aminopurine
• 8-Azaadenine
• 8-Azapurine
• 8-Azapurine, 6-amino-
• Adenine, 8-aza-
• Nsc 32797
• 7-Amino-1H-triazolo(4,5-d)pyrimidine
• 8-AZAADENINE CRYSTALLINE
• 6-Amino-8-azapurine, 8-Aza-6-aminopurine
• H-1,2,3-TRIAZOLO[4,5-D]PYRIMIDIN-7-AMINE
• 8-AZAADENINE 99-100%
• 1H-1,2,3-Triazolo[4,5-d]pyrimidin-7-amine (9CI)

8-Azaadenine

CAS: 1123-54-2

Formula: C₄H₄N₆

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 136.12

Ref: 3B-A0552

8-Azaadenine

CAS: 1123-54-2

Formula: C₄H₄N₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 136.1148

Ref: IN-DA003NHH

8-Azaadenine

CAS: 1123-54-2

8-Azaadenine

Purity: ≥98%

Molecular weight: 136.11g/mol

Ref: 54-BUP16511

3H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-amine

CAS: 1123-54-2

3H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-amine

Formula: C₄H₄N₆

Purity: 98%

Color and Shape: pale yellow solid

Molecular weight: 136.12g/mol

Ref: 54-OR943587

8-Azaadenine

CAS: 1123-54-2

8-Azaadenine

Purity: ≥98%

Molecular weight: 136.11g/mol

Ref: 54-BUP19962

1H-[1,2,3]triazolo[4,5-d]pyrimidin-7-amine

CAS: 1123-54-2

Purity: 98%

Molecular weight: 136.1179962

Ref: 10-F790911

8-Azaadenine

CAS: 1123-54-2

8-Azaadenine is an analog of adenine that binds to the purine receptor in the cell membrane. It has been shown to inhibit the growth of bacterial strains, such as Klebsiella pneumoniae and Staphylococcus aureus, by targeting their DNA gyrase and topoisomerase IV. 8-Azaadenine has also been shown to have a high resistance to bacterial mutants resistant to other antibiotics. It has been found that the nitrogen atoms in 8-azaadenine are important for its biological properties. The optimum pH for this antibiotic is 7.4.

Formula: C₄H₄N₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 136.12 g/mol

Ref: 3D-FA15767

3H-[1,2,3]Triazolo[4,5-d]pyrimidin-7-amine

CAS: 1123-54-2

Formula: C₄H₄N₆

Purity: 97.0%

Color and Shape: Solid

Molecular weight: 136.118

Ref: 10-F065082

8-Azaadenine

CAS: 1123-54-2

8-Azaadenine (NSC-32797) is an inhibitor of xanthine oxidase with IC50 of 0.54 μM and Ki of 0.66 μM.

Formula: C₄H₄N₆

Purity: 99.68%

Color and Shape: White Powder

Molecular weight: 136.11

Ref: TM-T20042

8-Azaadenine

Controlled Product

CAS: 1123-54-2

Formula: C₄H₄N₆

Color and Shape: Neat

Molecular weight: 136.11

Ref: TR-A797308