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CAS 112344-52-2

:

Flobufen

Description:
Flobufen is a non-steroidal anti-inflammatory drug (NSAID) primarily used for its analgesic and anti-inflammatory properties. It is characterized by its ability to inhibit cyclooxygenase enzymes, which play a crucial role in the synthesis of prostaglandins, compounds involved in inflammation and pain signaling. Flobufen is often utilized in the treatment of various conditions, including arthritis and other inflammatory disorders. The substance is typically administered in oral form and is known for its relatively rapid onset of action. Its pharmacokinetics involve absorption in the gastrointestinal tract, with metabolism occurring primarily in the liver. The drug's safety profile includes potential side effects common to NSAIDs, such as gastrointestinal discomfort, cardiovascular risks, and renal effects, necessitating careful monitoring during use. As with any medication, it is essential to follow dosing guidelines and consult healthcare professionals for personalized advice, particularly for individuals with pre-existing health conditions or those taking other medications.
Formula:C17H14F2O3
InChI:InChI=1S/C17H14F2O3/c1-10(17(21)22)8-16(20)12-4-2-11(3-5-12)14-7-6-13(18)9-15(14)19/h2-7,9-10H,8H2,1H3,(H,21,22)
InChI key:InChIKey=FIKVYIRIUOFLLR-UHFFFAOYSA-N
SMILES:FC1=C(C=CC(F)=C1)C2=CC=C(C(CC(C(O)=O)C)=O)C=C2
Synonyms:
  • 4-(2′,4′-Difluorobiphenyl-4-yl)-4-oxo-2-methylbutanoic acid
  • Flobufen
  • [1,1′-Biphenyl]-4-butanoic acid, 2′,4′-difluoro-α-methyl-γ-oxo-
  • 2′,4′-Difluoro-α-methyl-γ-oxo[1,1′-biphenyl]-4-butanoic acid
  • VUFB 16066
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