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CAS 112362-50-2

:

Dalfopristin

Description:
Dalfopristin is a semi-synthetic antibiotic that belongs to the streptogramin class of antibiotics, primarily used in combination with quinupristin for the treatment of certain bacterial infections, particularly those caused by Gram-positive bacteria, including resistant strains like vancomycin-resistant Enterococcus (VRE). It functions by inhibiting bacterial protein synthesis, thereby exerting its antimicrobial effects. Dalfopristin is typically administered intravenously and is known for its synergistic action when combined with quinupristin, enhancing its efficacy against resistant pathogens. The compound is characterized by its complex structure, which includes a cyclic peptide moiety, contributing to its unique mechanism of action. Dalfopristin is generally well-tolerated, but it may cause side effects such as gastrointestinal disturbances and potential interactions with other medications due to its metabolism via the cytochrome P450 system. Its use is often reserved for serious infections due to the emergence of antibiotic resistance, highlighting the importance of judicious antibiotic use in clinical settings.
Formula:C34H50N4O9S
InChI:InChI=1/C34H50N4O9S/c1-7-37(8-2)16-17-48(44,45)28-13-15-38-31(28)34(43)47-32(22(3)4)24(6)11-12-29(41)35-14-9-10-23(5)18-25(39)19-26(40)20-30-36-27(21-46-30)33(38)42/h9-12,18,21-22,24-25,28,31-32,39H,7-8,13-17,19-20H2,1-6H3,(H,35,41)/b10-9-,12-11-,23-18-/t24-,25-,28-,31-,32-/m1/s1
InChI key:InChIKey=SUYRLXYYZQTJHF-VMBLUXKRSA-N
SMILES:CCN(CC)CCS(=O)(=O)[C@@H]1CCN2[C@H]1C(=O)O[C@H](C(C)C)[C@H](C)C=CC(=NCC=CC(=C[C@H](CC(=O)Cc1nc(co1)C2=O)O)C)O
Synonyms:
  • (3R,4R,5E,10E,12E,14S,26R,26aS)-26-((2-(Diethylamino)ethyl)sulfonyl)-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-nitrilo-1H,22H-pyrrolo(2,1-c)(1,8,4,19)dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
  • (3R,4R,5E,10E,12E,14S,26R,26aS)-26-[[2-(Diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-3H-21,18-nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
  • (3R,4R,5Z,10Z,12Z,14S,26R,26aS)-26-{[2-(diethylamino)ethyl]sulfonyl}-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-8,9,14,15,24,25,26,26a-octahydro-1H,3H,22H-21,18-(azeno)pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone
  • 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine, virginiamycin M<sub>1</sub> deriv.
  • 3H-21,18-Nitrilo-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosine-1,7,16,22(4H,17H)-tetrone, 26-[[2-(diethylamino)ethyl]sulfonyl]-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-4,12-dimethyl-3-(1-methylethyl)-, (3R,4R,5E,10E,12E,14S,26R,26aS)-
  • Dalfopristin [USAN:INN]
  • Dalfopristina
  • Dalfopristina [INN-Spanish]
  • Dalfopristine
  • Dalfopristine [INN-French]
  • See more synonyms
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Found 6 products.
  • Dalfopristin
    Indagoo
    + Info

    Dalfopristin

    CAS:
    Formula:C34H50N4O9S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:690.8472

    Ref: IN-DA008T3Q

    1mg
    334.00€
    5mg
    195.00€
    25mg
    359.00€
  • Dalfopristin
    Apollo Scientific
    + Info

    Dalfopristin

    CAS:

    Dalfopristin

    Purity:≥98%
    Molecular weight:690.85g/mol

    Ref: 54-BUP04552

    1mg
    To inquire
  • Dalfopristin
    Apollo Scientific
    + Info

    Dalfopristin

    CAS:
    Dalfopristin
    Purity:98%
    Molecular weight:690.85g/mol

    Ref: 54-OR1023839

    100mg
    994.00€
    250mg
    1,560.00€
  • Dalfopristin
    Glentham
    + Info

    Dalfopristin

    CAS:
    Formula:C34H50N4O9S
    Purity:≥ 98.0%
    Color and Shape:White to yellow solid
    Molecular weight:690.8472

    Ref: 7W-GA0156

    ne
    To inquire
  • Dalfopristin
    TLC
    + Info

    Dalfopristin

    CAS:
    Formula:C34H50N4O9S
    Molecular weight:690.85

    Ref: 4Z-D-305001

    5mg
    To inquire
    10mg
    To inquire
    25mg
    To inquire
    50mg
    To inquire
    100mg
    To inquire
  • Dalfopristin
    Targetmol
    + Info

    Dalfopristin

    CAS:
    Dalfopristin (RP54476), a semi-synthetic streptogramin, treats multi-resistant Enterococcus faecium.
    Formula:C34H50N4O9S
    Purity:95.48%
    Color and Shape:Solid
    Molecular weight:690.85

    Ref: TM-TQ0152

    1mg
    105.00€
    5mg
    215.00€
    10mg
    344.00€
    25mg
    623.00€
    50mg
    888.00€
    100mg
    1,224.00€
    1mL*10mM (DMSO)
    326.00€