CAS: 1123837-84-2 - N-[3-Fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide

Formula: C₃₃H₂₉F₂N₅O₄S

InChI: InChI=1S/C33H29F2N5O4S/c1-43-15-14-36-18-20-2-8-25(38-19-20)29-17-26-30(45-29)28(10-13-37-26)44-27-9-7-23(16-24(27)35)40-32(42)33(11-12-33)31(41)39-22-5-3-21(34)4-6-22/h2-10,13,16-17,19,36H,11-12,14-15,18H2,1H3,(H,39,41)(H,40,42)

InChI key: InChIKey=WLAVZAAODLTUSW-UHFFFAOYSA-N

SMILES: O=C(NC1=CC=C(F)C=C1)C2(C(=O)NC3=CC=C(OC=4C=CN=C5C=C(SC54)C=6N=CC(=CC6)CNCCOC)C(F)=C3)CC2

Synonyms:

• MGCD 516
• N-[3-Fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-1,1-cyclopropanedicarboxamide
• N-(3-fluoro-4-{[2-(5-{[(2-methoxyethyl)amino]methyl}pyridin-2-yl)thieno[3,2-b]pyridin-7-yl]oxy}phenyl)-N′-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide
• 1,1-Cyclopropanedicarboxamide, N-[3-fluoro-4-[[2-[5-[[(2-methoxyethyl)amino]methyl]-2-pyridinyl]thieno[3,2-b]pyridin-7-yl]oxy]phenyl]-N′-(4-fluorophenyl)-
• Sitravatinib

Sitravatinib

CAS: 1123837-84-2

• Formula: C₃₃H₂₉F₂N₅O₄S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 629.6763

Sitravatinib

CAS: 1123837-84-2

Sitravatinib (MGCD516) (MGCD516) is an inhibitor targeting multiple RTKs involved in driving sarcoma cell growth, …

• Formula: C₃₃H₂₉F₂N₅O₄S
• Purity: 98.9% - 99.74%
• Color and Shape: Solid
• Molecular weight: 629.68

Sitravatinib

CAS: 1123837-84-2

Inhibits multiple receptor tyrosine kinases (RTKs), including c-Kit, PDGFRβ, PDGFRα, c-Met, and Axl. Sitravatinib inhibits …

• Formula: C₃₃H₂₉F₂N₅O₄S
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 629.68 g/mol

MGCD 516

CAS: 1123837-84-2

• Formula: C₃₃H₂₉F₂N₅O₄S
• Color and Shape: Neat
• Molecular weight: 629.676