CAS 1125-40-2

3-methyl-1H-indol-5-ol

Description:

3-Methyl-1H-indol-5-ol, with the CAS number 1125-40-2, is an organic compound that belongs to the indole family, characterized by a fused bicyclic structure containing a benzene ring and a pyrrole ring. This compound features a hydroxyl group (-OH) at the 5-position and a methyl group (-CH3) at the 3-position of the indole structure, which contributes to its unique chemical properties. It is typically a solid at room temperature and may exhibit moderate solubility in polar solvents due to the presence of the hydroxyl group. The compound is of interest in various fields, including medicinal chemistry and biochemistry, due to its potential biological activities, such as antimicrobial and antioxidant properties. Additionally, its structure allows for various chemical modifications, making it a useful intermediate in organic synthesis. Safety data should be consulted for handling, as with many organic compounds, it may pose health risks if not managed properly.

Formula: C₉H₉NO

InChI: InChI=1S/C9H9NO/c1-6-5-10-9-3-2-7(11)4-8(6)9/h2-5,10-11H,1H3

InChI key: InChIKey=NPHFOFOYWYLBTF-UHFFFAOYSA-N

SMILES: CC=1C=2C(=CC=C(O)C2)NC1

Synonyms:

• 1H-indol-5-ol, 3-methyl-
• 3-Methyl-5-hydroxyindole
• 5-Hydroxy-3-methylindole
• 5-Hydroxyskatole
• Indol-5-ol, 3-methyl-
• Lumogen no. 1
• 3-Methyl-1H-indol-5-ol
• 3-Methyl-1H-indol-5-ol

3-Methyl-1H-indol-5-ol

CAS: 1125-40-2

Formula: C₉H₉NO

Purity: 98%

Color and Shape: Solid

Molecular weight: 147.1739

Ref: IN-DA007AM1

5-Hydroxy-3-methylindole

CAS: 1125-40-2

5-Hydroxy-3-methylindole

Purity: 98%

Molecular weight: 147.17g/mol

Ref: 54-OR940620

5-Hydroxy-3-methylindole

CAS: 1125-40-2

Formula: C₉H₉NO

Purity: 95%

Color and Shape: Solid

Molecular weight: 147.177

Ref: 10-F225512

5-Hydroxy-3-methylindole

CAS: 1125-40-2

5-Hydroxy-3-methylindole (5HMI) is a metabolite of the drug tamoxifen, which is used for the treatment of breast cancer. It is also found in urine samples and has been shown to be reactive with cytochrome P450 2E1 (CYP2E1). 5HMI has been shown to inhibit the activity of CYP2E1 in humans, rats, and mice. 5HMI has also been shown to have anti-epileptic properties in epileptics. This active form is metabolized by adipose tissue or liver cells through oxidation and conjugation with glucuronic acid. The human liver cells show constitutive androstane receptor (CAR) activation, which may be due to its ability to act as an agonist or partial agonist.

Formula: C₉H₉NO

Purity: Min. 96%

Color and Shape: Powder

Molecular weight: 147.17 g/mol

Ref: 3D-FH13802