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CAS 112529-15-4

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Pioglitazone Hydrochloride

Description:
Pioglitazone Hydrochloride is an antidiabetic medication primarily used to manage type 2 diabetes mellitus. It belongs to the thiazolidinedione class of drugs, which function as agonists of the peroxisome proliferator-activated receptor gamma (PPAR-γ). This mechanism enhances insulin sensitivity in muscle and adipose tissue, thereby improving glycemic control. The substance appears as a white to off-white crystalline powder, which is soluble in water and exhibits a moderate melting point. Its chemical formula is C19H20N2O3S·HCl, indicating the presence of a hydrochloride salt. Pioglitazone is typically administered orally and is often prescribed in conjunction with diet and exercise to optimize blood sugar levels. Common side effects may include weight gain, edema, and an increased risk of heart failure, necessitating careful monitoring of patients. Additionally, it is contraindicated in individuals with a history of heart failure or active bladder cancer. Overall, Pioglitazone Hydrochloride plays a significant role in diabetes management, but its use must be balanced with potential risks.
Formula:C19H20N2O3S·ClH
InChI:InChI=1S/C19H20N2O3S.ClH/c1-2-13-3-6-15(20-12-13)9-10-24-16-7-4-14(5-8-16)11-17-18(22)21-19(23)25-17;/h3-8,12,17H,2,9-11H2,1H3,(H,21,22,23);1H
InChI key:InChIKey=GHUUBYQTCDQWRA-UHFFFAOYSA-N
SMILES:C(C1C(=O)NC(=O)S1)C2=CC=C(OCCC3=CC=C(CC)C=N3)C=C2.Cl
Synonyms:
  • 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, hydrochloride (1:1)
  • 2,4-Thiazolidinedione, 5-[[4-[2-(5-ethyl-2-pyridinyl)ethoxy]phenyl]methyl]-, monohydrochloride
  • 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride
  • 5-[[4-2-(5-ethyl-2-pyridinyl)ethoxy]benzylidene]-2,4-thiazolidinedione Hydrochloride
  • 5-[[4-[2-(5-Ethyl-2-pyridinyl]ethoxy]phenyl]methyl]-2,4-thiazolidinedione N-Oxide
  • 5-{4-[2-(5-Ethyl-1-Oxidopyridin-2-Yl)Ethoxy]Benzyl}-1,3-Thiazolidine-2,4-Dione
  • Actos
  • Ad 4833
  • Glidipion
  • Glustin
  • See more synonyms
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Found 18 products.
  • Pioglitazone Hydrochloride

    CAS:
    Formula:C19H20N2O3S·HCl
    Purity:>98.0%(HPLC)(N)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:392.90

    Ref: 3B-P1901

    5g
    83.00€
    25g
    288.00€
  • PIOGLITAZONE HYDROCHLORIDE CRS

    CAS:
    <p>PIOGLITAZONE HYDROCHLORIDE CRS</p>
    Formula:C19H21ClN2O3S
    Color and Shape:Added Modified
    Molecular weight:392.8996

    Ref: 41-Y0001520

    120mg
    115.00€
  • Pioglitazone hydrochloride

    CAS:
    Pioglitazone hydrochloride
    Formula:C19H21CIN2O3S
    Purity:100.0%
    Color and Shape:Off-White
    Molecular weight:496.03176

    Ref: 47-1298

    100mg
    242.00€
  • PIOGLITAZONE FOR SYSTEM SUITABILITY CRS

    CAS:
    <p>PIOGLITAZONE FOR SYSTEM SUITABILITY CRS</p>
    Formula:C19H21ClN2O3S
    Molecular weight:392.8996

    Ref: 41-Y0001519

    15mg
    115.00€
  • Pioglitazone Hydrochloride

    CAS:
    <p>Compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure</p>
    Formula:C19H20N2O3S·HCl
    Color and Shape:White Powder
    Molecular weight:356.11946
  • 5-[4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl]thiazolidine-2,4-dione hydrochloride

    CAS:
    Formula:C19H21ClN2O3S
    Purity:98%
    Color and Shape:Solid
    Molecular weight:392.8996

    Ref: IN-DA0037YF

    1g
    26.00€
    5g
    44.00€
    10g
    62.00€
    1kg
    To inquire
    25g
    77.00€
    100g
    153.00€
    25mg
    20.00€
    500g
    674.00€
    250mg
    25.00€
  • Pioglitazone hydrochloride

    CAS:
    <p>Pioglitazone hydrochloride (AD 4833) is the hydrochloride salt of an orally-active thiazolidinedione with antidiabetic properties and potential antineoplastic</p>
    Formula:C19H20N2O3S·HCl
    Purity:99.64% - >99.99%
    Color and Shape:White Crystals Or Crystalline Powder
    Molecular weight:392.90
  • Pioglitazone hydrochloride

    CAS:
    Formula:C19H20N2O3S·HCl
    Purity:98.5 - 101.5 % (anhydrous basis)
    Color and Shape:White to off-white crystalline powder
    Molecular weight:392.90

    Ref: 7W-GP3582

    1g
    53.00€
  • Pioglitazone HCl

    CAS:
    Formula:C19H20N2O3S·HCl
    Color and Shape:White To Off-White Solid
    Molecular weight:356.44 36.46

    Ref: 4Z-P-1011

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Pioglitazone Hydrochloride

    CAS:
    <p>Pioglitazone Hydrochloride</p>
    Purity:99%
    Molecular weight:392.90g/mol

    Ref: 54-OR1014672

    1g
    32.00€
    5g
    36.00€
    25g
    61.00€
    100g
    194.00€
    500g
    669.00€
    2.5kg
    2,644.00€
  • Pioglitazone hydrochloride

    CAS:
    <p>Pioglitazone hydrochloride</p>
    Purity:≥98%
    Molecular weight:392.9g/mol

    Ref: 54-BUP17061

    2g
    284.00€
    5g
    466.00€
    50mg
    57.00€
    100mg
    80.00€
    200mg
    111.00€
    500mg
    178.00€
  • Pioglitazone Hydrochloride

    Controlled Product
    CAS:
    Formula:C19H20N2O3S·ClH
    Color and Shape:Neat
    Molecular weight:392.90

    Ref: 04-C16216000

    100mg
    111.00€
  • Ref: 86-MM0616.00

    250mg
    849.00€
  • Ref: 2K-1114800021

    160mg
    To inquire
  • 5-{4-[2-(5-Ethyl-pyridin-2-yl)-ethoxy]-benzyl}-thiazolidine-2,4-dione hydrochloride

    CAS:
    Purity:97.0%
    Color and Shape:Solid
    Molecular weight:392.8999938964844

    Ref: 10-F036553

    1g
    28.00€
    5g
    To inquire
    10g
    To inquire
    25g
    79.00€
    50g
    To inquire
    100g
    175.00€
    250mg
    To inquire
  • Pioglitazone Hydrochloride

    CAS:
    <p>Applications Pioglitazone Hydrochloride is used as an antidiabetic.<br>References Hofmann, C., et al.: Endocrinology, 129, 1915(1991), Kobayashi, M., et al.: Diabetes, 41, 476 (1992), Kawaamori, R., et al.,: Diabetes Res. Clin. Pract., 41, 35 (1998)<br></p>
    Formula:C19H20N2O3S·ClH
    Color and Shape:Off-White
    Molecular weight:392.90

    Ref: TR-P471000

    1g
    204.00€
    10mg
    113.00€
    100mg
    128.00€
  • Pioglitazone HCl

    CAS:
    <p>Agonist of peroxisome proliferator-activated receptor-γ (PPARγ), useful for the treatment and prevention of type 2 diabetes mellitus. It belongs to the class of thiazolidinediones (TZDs), which increase insulin sensitivity and glucose uptake in peripheral tissues. It reduces the risk of cardiovascular disease and was shown to atheroprotective and anti-inflammatory effects in animal models.</p>
    Formula:C19H20N2O3S·HCl
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:392.91 g/mol

    Ref: 3D-FP02645

    5g
    208.00€
    10g
    349.00€
    25g
    684.00€
    50g
    1,141.00€
  • Pioglitazone HCl - Bio-X ™

    CAS:
    <p>Pioglitazone is a thiazolidinedione drug that is used in combination with diet change and exercise to treat glycemic levels in patients with type 2 diabetes mellitus. This drug is an agonist of peroxisome proliferator-activated receptor-gamma and increases glucose uptake. In animal studies, Pioglitazone has shown to have anti-inflammatory properties.</p>
    Formula:C19H20N2O3S•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:392.9 g/mol

    Ref: 3D-BP164272

    100mg
    134.00€