CAS 112649-21-5

Garcinone E

Description:

Garcinone E is a naturally occurring chemical compound classified as a xanthone, which is a type of polyphenolic compound. It is primarily derived from the Garcinia species, particularly Garcinia mangostana, known for its potential health benefits. Garcinone E exhibits a range of biological activities, including antioxidant, anti-inflammatory, and anticancer properties, making it of interest in pharmacological research. The compound's structure features a fused ring system that contributes to its reactivity and interaction with biological targets. In terms of solubility, Garcinone E is generally soluble in organic solvents, which is typical for many xanthones, but may have limited solubility in water. Its potential applications in medicine and nutraceuticals are being explored, particularly in the context of its therapeutic effects. As with many natural products, further studies are necessary to fully elucidate its mechanisms of action and potential benefits in human health.

Formula: C₂₈H₃₂O₆

InChI: InChI=1S/C28H32O6/c1-14(2)7-10-17-20(29)13-21-23(24(17)30)27(33)22-18(11-8-15(3)4)25(31)26(32)19(28(22)34-21)12-9-16(5)6/h7-9,13,29-32H,10-12H2,1-6H3

InChI key: InChIKey=WVJYEKGQSBGNRP-UHFFFAOYSA-N

SMILES: C(C=C(C)C)C1=C2C(=C(CC=C(C)C)C(O)=C1O)OC=3C(C2=O)=C(O)C(CC=C(C)C)=C(O)C3

Synonyms:

• Garcinone E
• 9H-Xanthen-9-one, 2,3,6,8-tetrahydroxy-1,4,7-tris(3-methyl-2-buten-1-yl)-
• 9H-Xanthen-9-one,2,3,6,8-tetrahydroxy-1,4,7-tris(3-methyl-2-butenyl)- (9CI)
• Garcinone E
• 9H-Xanthen-9-one, 2,3,6,8-tetrahydroxy-1,4,7-tris(3-methyl-2-butenyl)-
• 2,3,6,8-Tetrahydroxy-1,4,7-tris(3-methyl-2-buten-1-yl)-9H-xanthen-9-one
• 7-O-Demethyl-5-prenyl-α-mangostin

Garcinone E

CAS: 112649-21-5

Garcinone E is active constituents in the anticomplement assay used.

Formula: C₂₈H₃₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 464.55

Ref: TM-TN4113

Garcinone E

CAS: 112649-21-5

Garcinone E is a natural compound classified as a xanthone, which is derived from the fruit of the Garcinia species, particularly Garcinia mangostana. This source is renowned for its rich phytochemical composition, which includes numerous bioactive molecules. Garcinone E, in particular, exhibits a mode of action primarily associated with its ability to interfere with cancer cell proliferation and induce apoptosis. The compound operates by modulating various signaling pathways, including those involved in cell cycle regulation and apoptosis, thus demonstrating significant antiproliferative effects against certain cancer cell lines.

Formula: C₂₈H₃₂O₆

Purity: Min. 95%

Molecular weight: 464.50 g/mol

Ref: 3D-MEA64921