CAS 112704-79-7

4-Bromo-2-fluorobenzoic acid

Description:

4-Bromo-2-fluorobenzoic acid is an aromatic carboxylic acid characterized by the presence of both bromine and fluorine substituents on the benzene ring. The compound features a bromine atom at the para position (4-position) and a fluorine atom at the ortho position (2-position) relative to the carboxylic acid group (-COOH). This substitution pattern influences its chemical reactivity and physical properties, such as solubility and boiling point. The presence of halogens typically enhances the acidity of the carboxylic acid due to their electronegative nature, which can stabilize the carboxylate ion formed upon deprotonation. 4-Bromo-2-fluorobenzoic acid is often used in organic synthesis and pharmaceutical research, serving as an intermediate in the preparation of various biologically active compounds. Its unique combination of functional groups makes it a valuable compound for studying structure-activity relationships in medicinal chemistry. Safety precautions should be observed when handling this compound, as it may pose health risks due to its halogenated nature.

Formula: C₇H₄BrFO₂

InChI: InChI=1S/C7H4BrFO2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3H,(H,10,11)

InChI key: InChIKey=ZQQSRVPOAHYHEL-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(F)C=C(Br)C=C1

Synonyms:

• 1-(4-Bromo-2-Fluorophenyl)Methanamine
• 2-Fluoro-4-Bromobenzoic Acid
• 2-Fluoro-4-bromobenzoicacid
• 4-Bromo-2-Fluoro-Benzoic Acid
• 4-Bromo-2-Fluorobenzoate
• 4-Bromo-2-fluorobenzoic
• 4-Bromo-2-fluorobenzoicacid
• Benzoic acid, 4-bromo-2-fluoro-
• Buttpark 18\02-86
• NSC 190364
• Rarechem Al Bo 0754

4-Bromo-2-fluorobenzoic Acid

CAS: 112704-79-7

Formula: C₇H₄BrFO₂

Purity: >99.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 219.01

Ref: 3B-B1950

4-Bromo-2-fluorobenzoic acid, 98%

CAS: 112704-79-7

4-Bromo-2-fluorobenzoic acid may be used in the synthesis of biaryl intermediates by palladium-mediated coupling with various aryl boronic acids This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer

Formula: C₇H₃BrFO₂

Purity: 98%

Color and Shape: Powder, White to pale cream

Molecular weight: 218.00

Ref: 02-B20118

4-Bromo-2-fluorobenzoic acid

CAS: 112704-79-7

Formula: C₇H₄BrFO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 219.0079

Ref: IN-DA0033XE

4-Bromo-2-fluorobenzoic acid

CAS: 112704-79-7

4-Bromo-2-fluorobenzoic acid

Formula: C₇H₄BrFO₂

Purity: 98%

Color and Shape: white powder

Molecular weight: 219.01g/mol

Ref: 54-PC3994

Enzalutamide Impurity A

CAS: 112704-79-7

Formula: C₇H₄BrFO₂

Molecular weight: 219.01

Ref: 4Z-E-068006

Enzalutamide EP Impurity A

CAS: 112704-79-7

Formula: C₇H₄BrFO₂

Molecular weight: 219

Ref: ST-EA-CP-E16001

4-Bromo-2-fluorobenzoic acid

CAS: 112704-79-7

4-Bromo-2-fluorobenzoic acid is an organic solvent that is used in the introduction of 2-aminoisobutyric acid. The reaction solution is typically heated and contains a small amount of either chloride, sulfoxide, or both. Various analytical methods can be used to determine the yield of the acylation reaction. 4-Bromo-2-fluorobenzoic acid's ligand can be converted to an acid chloride with a Grignard reagent and then reacted with carboxylate to form an ester. This ester reacts with amines to form amides, which are used as pharmaceuticals and intermediates for various other reactions. 4-Bromo-2-fluorobenzoic acid inhibits bacterial growth by binding to glutamine synthetase, thereby inhibiting protein synthesis.

Formula: C₇H₄BrFO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 219.01 g/mol

Ref: 3D-FB36908

4-Bromo-2-fluorobenzoic acid

CAS: 112704-79-7

Formula: C₇H₄BrFO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 219.009

Ref: 10-F008669

4-Bromo-2-fluorobenzoic Acid

Controlled Product

CAS: 112704-79-7

Applications 4-Bromo-2-fluorobenzoic Acid is a halogenated derivative of benzoic acid. 4-Bromo-2-fluorobenzoic Acid is used in the synthesis of pharmaceutically significant products such as d-Amino acid oxidase inhibitors.
References Katane, M., et al.: J. Med. Chem., 56, 1894 (2013); Vasbinder, M.M., et al.: J. Med. Chem., 56, 1996 (2013);

Formula: C₇H₄BrFO₂

Color and Shape: Neat

Molecular weight: 219.01

Ref: TR-B684620