CAS 112725-22-1

N-succinimidyl-3-(tri-n-butylstannyl)benzoate

Description:

N-succinimidyl-3-(tri-n-butylstannyl)benzoate is a chemical compound characterized by its unique structure, which includes a succinimide moiety and a tri-n-butylstannyl group attached to a benzoate. This compound is typically used in organic synthesis and bioconjugation applications, particularly in the field of medicinal chemistry and materials science. The presence of the succinimidyl group allows for the formation of stable amide bonds with nucleophiles, making it useful for labeling biomolecules or modifying surfaces. The tri-n-butylstannyl group provides a hydrophobic character and can facilitate the incorporation of the compound into various organic matrices. Additionally, the compound's stability and reactivity under specific conditions make it a valuable tool in chemical research. However, due to the presence of tin, it is important to handle it with care, considering the potential environmental and health impacts associated with organotin compounds. Overall, N-succinimidyl-3-(tri-n-butylstannyl)benzoate is a versatile reagent in synthetic chemistry with applications in diverse fields.

Formula: C₂₃H₃₅NO₄Sn

InChI: InChI=1/C11H8NO4.3C4H9.Sn/c13-9-6-7-10(14)12(9)16-11(15)8-4-2-1-3-5-8;3*1-3-4-2;/h1-2,4-5H,6-7H2;3*1,3-4H2,2H3;/rC23H35NO4Sn/c1-4-7-15-29(16-8-5-2,17-9-6-3)20-12-10-11-19(18-20)23(27)28-24-21(25)13-14-22(24)26/h10-12,18H,4-9,13-17H2,1-3H3

SMILES: CCCC[Sn](CCCC)(CCCC)c1cccc(c1)C(=O)ON1C(=O)CCC1=O

Synonyms:

• Stbsb
• m-Buate
• 2,5-Pyrrolidinedione, 1-((3-(tributylstannyl)benzoyl)oxy)-
• 1-{[3-(Tributylstannanyl)Benzoyl]Oxy}Pyrrolidine-2,5-Dione

Succinimidyl 3-(tri-n-butylstannyl)benzoate

Controlled Product

CAS: 112725-22-1

Succinimidyl 3-(tri-n-butylstannyl)benzoate (SBTB) is a potent oxidant that can be used in the regression of radiation damage. SBTB is synthesised by reacting tri-n-butyl tin oxide with succinic anhydride and tert-butanol in the presence of base. This active form is then reacted with a protein or peptide to form a succinimidyl ester. The resulting compound has been shown to be effective against many types of cancer, including human gliomas, when coupled with monoclonal antibodies targeting tumor cells. The uptake of SBTB into cells is largely determined by the amount of hydrophobic surface area on the cell membrane and its solubility in water, which has been shown to be optimized using NMR spectroscopy. SBTB also inhibits the growth of Stachybotrys chartarum and other fungi that are known to produce mycotoxins

Formula: C₂₃H₃₅NSnO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 508.24 g/mol

Ref: 3D-FS52846

Succinimidyl 3-(Tri-n-butylstannyl)benzoate

Controlled Product

CAS: 112725-22-1

Formula: C₂₃H₃₅NSnO₄

Color and Shape: Neat

Molecular weight: 508.24

Ref: TR-S692038