CAS 112727-80-7

Renzapride

Description:

Renzapride is a chemical compound classified as a selective serotonin 5-HT4 receptor agonist and a 5-HT3 receptor antagonist. It is primarily investigated for its potential therapeutic applications in gastrointestinal disorders, particularly in enhancing gastrointestinal motility and alleviating symptoms associated with conditions like irritable bowel syndrome. The molecular structure of Renzapride features a piperidine ring, which contributes to its pharmacological activity. Its mechanism of action involves stimulating the 5-HT4 receptors, leading to increased peristalsis and improved gut transit, while simultaneously blocking 5-HT3 receptors, which can help reduce nausea and discomfort. Renzapride has been studied for its efficacy and safety profile in clinical settings, although it may not be widely available in all markets. As with many pharmacological agents, potential side effects can include gastrointestinal disturbances, headache, and dizziness. Overall, Renzapride represents a promising approach in the management of functional gastrointestinal disorders, although further research may be necessary to fully establish its clinical utility.

Formula: C₁₆H₂₂ClN₃O₂

InChI: InChI=1/C16H22ClN3O2/c1-22-15-8-13(18)12(17)7-11(15)16(21)19-14-4-6-20-5-2-3-10(14)9-20/h7-8,10,14H,2-6,9,18H2,1H3,(H,19,21)/t10-,14+/s2

InChI key: InChIKey=GZSKEXSLDPEFPT-MOVNSBPVNA-N

SMILES: C(N[C@H]1[C@@]2(C[N@](CC1)CCC2)[H])(=O)C3=C(OC)C=C(N)C(Cl)=C3

Synonyms:

• (( -)-endo)-4-Amino-5-chloro-2-methoxy-N-(1-azabicyclo(3.3.1)non-4-yl)benzamide
• 1-Azabicyclo[3.3.1]nonane, benzamide deriv.
• 4-Amino-N-1-azabicyclo(3.3.1)non-4-yl-5-chloro-2-methoxybenzamide endo-
• 4-amino-N-[(4S,5S)-1-azabicyclo[3.3.1]non-4-yl]-5-chloro-2-methoxybenzamide
• Benzamide, 4-amino-N-(1R,4S,5R)-1-azabicyclo[3.3.1]non-4-yl-5-chloro-2-methoxy-, rel-
• Benzamide, 4-amino-N-1-azabicyclo(3.3.1)non-4-yl-5-chloro-2-methoxy-, endo-
• Renzaprida
• Renzaprida [INN-Spanish]
• Renzapride [INN]
• Renzapridum
• Renzapridum [INN-Latin]
• rel-4-Amino-N-(1R,4S,5R)-1-azabicyclo[3.3.1]non-4-yl-5-chloro-2-methoxybenzamide

Renzapride

CAS: 112727-80-7

Renzapride

Purity: ≥95%

Molecular weight: 323.82g/mol

Ref: 54-BUP07443

Dalotutumab (Renzapride)

CAS: 112727-80-7

Formula: C₁₆H₂₂ClN₃O₂

Molecular weight: 323.82

Ref: 4Z-D-105003

Renzapride

CAS: 112727-80-7

Renzapride (BRL 24924) is a mixed 5-hydroxytryptamine type 4 (5-HT4) agonist and 5-HT3 receptor antagonist used in the study of irritable bowel syndrome.

Formula: C₁₆H₂₂ClN₃O₂

Purity: 98.97% - 99.09%

Color and Shape: Solid

Molecular weight: 323.82

Ref: TM-T38507