CAS 112780-67-3

3-FLUORO-4-METHOXYPHENYLMAGNESIUM BROMIDE

Description:

3-Fluoro-4-methoxyphenylmagnesium bromide is a Grignard reagent, which is an organomagnesium compound commonly used in organic synthesis. This compound features a phenyl group substituted with a fluorine atom and a methoxy group, making it a valuable intermediate in the synthesis of various organic compounds. The presence of the fluorine atom can influence the reactivity and selectivity of the reagent in nucleophilic addition reactions, while the methoxy group can enhance solubility and stability. As a Grignard reagent, it is highly reactive, particularly with electrophiles, and must be handled under anhydrous conditions to prevent hydrolysis by moisture. The compound is typically prepared by reacting 3-fluoro-4-methoxyphenyl bromide with magnesium in an ether solvent. Its applications include the synthesis of alcohols, ketones, and other functionalized organic molecules, making it a crucial tool in synthetic organic chemistry. Proper safety precautions should be taken when handling this reagent due to its reactivity and potential hazards.

Formula: C₇H₆BrFMgO

InChI: InChI=1/C7H6FO.BrH.Mg/c1-9-7-5-3-2-4-6(7)8;;/h3-5H,1H3;1H;/q-1;;+2/p-1

SMILES: COC1=CC=C=C[C-]1F.Br.[Mg]

Synonyms:

• 3-Fluoro-4-Methoxyphenylmagnesium Bromide, 0.5M Solution In Tetrahydrofuran
• Magnesium Bromide 3-Fluoro-4-Methoxybenzenide

3-Fluoro-4-methoxyphenylmagnesium bromide 0.5M solution in THF

CAS: 112780-67-3

3-Fluoro-4-methoxyphenylmagnesium bromide 0.5M solution in THF

Purity: ≥95%

Molecular weight: 229.33g/mol

Ref: 54-PC2304