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Letrozole

CAS 112809-51-5: Letrozole

Description:Letrozole is a non-steroidal aromatase inhibitor primarily used in the treatment of hormone receptor-positive breast cancer in postmenopausal women. Its mechanism of action involves the inhibition of aromatase, an enzyme responsible for converting androgens into estrogens, thereby reducing estrogen levels in the body. This reduction is crucial as many breast cancers are fueled by estrogen. Letrozole is typically administered orally and is known for its relatively favorable side effect profile compared to other hormonal therapies. Common side effects may include hot flashes, joint pain, fatigue, and potential bone density loss. The chemical structure of letrozole includes a triazole ring, contributing to its pharmacological properties. It is classified under the category of antineoplastic agents and is often part of adjuvant therapy following surgery or as a first-line treatment for advanced breast cancer. Letrozole's efficacy and safety have made it a standard option in breast cancer management, and ongoing research continues to explore its potential in other malignancies and therapeutic contexts.

Formula:C17H11N5

InChI:InChI=1S/C17H11N5/c18-9-13-1-5-15(6-2-13)17(22-12-20-11-21-22)16-7-3-14(10-19)4-8-16/h1-8,11-12,17H

InChI key:InChIKey=HPJKCIUCZWXJDR-UHFFFAOYSA-N

SMILES:N#CC1=CC=C(C=C1)C(C2=CC=C(C#N)C=C2)N3N=CN=C3

  • Synonyms:
  • 4,4'-(1h-1,2,4-Triazol-1-Ylmethylene) Bis-Benzonitrile
  • 4,4'-(1h-1,2,4-Triazol-1-Ylmethylene)Bisbenzonitrile
  • 4,4′-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile
  • 4-[1-(4-Cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile
  • Benzonitrile, 4,4′-(1H-1,2,4-triazol-1-ylmethylene)bis-
  • Cgs 20267
  • Femara
  • Lelrozol
  • Lerozole
  • Letocor
  • See more synonyms
  • Letoripe
  • Letrazole
  • Letrof L Lil
  • Letroz
  • Letrozol
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Found 17 products.

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Ref: 3B-L0248

1g119.00 €
Estimated delivery in United States, on Wednesday 26 Feb 2025
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Letrozole

CAS:112809-51-5

Ref: AC-46319

1gTo inquire
Estimated delivery in United States, on Monday 3 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: 47-1234

100mg242.00 €
Estimated delivery in United States, on Monday 3 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: 45-1356971

200mg463.00 €
Estimated delivery in United States, on Tuesday 4 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: TM-T1590

25mg37.00 €
50mg50.00 €
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Ref: IN-DA0078V9

1g54.00 €
5g97.00 €
25g182.00 €
100g486.00 €
Estimated delivery in United States, on Wednesday 5 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: 4Z-L-163

5mgTo inquire
10mgTo inquire
25mgTo inquire
50mgTo inquire
100mgTo inquire
Estimated delivery in United States, on Thursday 6 Mar 2025
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Letrozol

CAS:112809-51-5

Ref: 54-OR98219

Undefined sizeTo inquire
Estimated delivery in United States, on Thursday 6 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: 04-C14628500

50mg115.00 €
Estimated delivery in United States, on Monday 10 Mar 2025
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Letrozole

Controlled Product
CAS:112809-51-5

Ref: 86-MM1143.00-0250

250mg781.00 €
Estimated delivery in United States, on Monday 10 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: 7W-GP1426

1g109.00 €
100mg53.00 €
Estimated delivery in United States, on Wednesday 12 Mar 2025
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1-[Bis(4-cyanophenyl)methyl]-1,2,4-triazole

CAS:112809-51-5

Ref: 10-F036495

1g39.00 €
5g94.00 €
25g265.00 €
100gTo inquire
Estimated delivery in United States, on Monday 17 Mar 2025
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Letrozole

CAS:112809-51-5

Ref: TR-L330100

10mg119.00 €
25mg135.00 €
50mg234.00 €
Estimated delivery in United States, on Monday 17 Mar 2025
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Letrozole - Bio-X ™

Controlled Product
CAS:112809-51-5

Ref: 3D-BL164620

50mg147.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Letrozole

Controlled Product
CAS:112809-51-5

Ref: 3D-FL24873

25g351.00 €
50g546.00 €
100g990.00 €
Estimated delivery in United States, on Tuesday 18 Mar 2025
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Letrozole

Controlled Product
CAS:112809-51-5

Ref: 3D-Q-201291

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Estimated delivery in United States, on Wednesday 16 Apr 2025
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