CAS 112811-59-3

Gatifloxacin

Description:

Gatifloxacin is a synthetic fluoroquinolone antibiotic characterized by its broad-spectrum antibacterial activity. It is primarily used to treat various bacterial infections, particularly those affecting the respiratory tract and urinary system. The chemical structure of gatifloxacin includes a bicyclic core with a fluorine atom, which enhances its potency against gram-positive and gram-negative bacteria. It exhibits a mechanism of action that involves the inhibition of bacterial DNA gyrase and topoisomerase IV, enzymes critical for DNA replication and repair. Gatifloxacin is typically administered orally and is known for its good bioavailability. However, it has been associated with potential side effects, including gastrointestinal disturbances and, in rare cases, tendon damage. Its use has declined in some regions due to safety concerns and the emergence of bacterial resistance. As with all antibiotics, it is essential to use gatifloxacin judiciously to minimize the risk of resistance development and to ensure its effectiveness in treating infections.

Formula: C₁₉H₂₂FN₃O₄

InChI: InChI=1S/C19H22FN3O4/c1-10-8-22(6-5-21-10)16-14(20)7-12-15(18(16)27-2)23(11-3-4-11)9-13(17(12)24)19(25)26/h7,9-11,21H,3-6,8H2,1-2H3,(H,25,26)

InChI key: InChIKey=XUBOMFCQGDBHNK-UHFFFAOYSA-N

SMILES: O(C)C1=C2N(C=C(C(O)=O)C(=O)C2=CC(F)=C1N3CC(C)NCC3)C4CC4

Synonyms:

• 1-Cyclopropyl-6-Fluoro-1,4-Dihydro-8-Methoxy-7-(3-Methyl-1-Piperazinyl)-4-Oxo-3-Quinolinecarboxylic Acid
• 1-Cyclopropyl-6-Fluoro-8-Methoxy-7-(3-Methylpiperazin-1-Yl)-4-Oxo-1,4-Dihydroquinoline-3-Carboxylic Acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid
• 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate
• 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-
• Am 1155
• Bms 206584-01
• G-Cebran
• Gaity
• Gatiflo
• Gatifloxin
• Gatilox
• Gatiquin
• Gatispan
• Pd 135432
• Tequin
• Tymer
• Zymar

Gatifloxacin

CAS: 112811-59-3

Drugs containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure

Formula: C₁₉H₂₂FN₃O₄

Color and Shape: White Light Yellow Powder

Molecular weight: 375.15943

Ref: 45-1288408

1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylicacid

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 375.3941

Ref: IN-DA001VAA

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin (CG5501), a fourth-gen fluoroquinolone antibiotic, blocks bacterial DNA gyrase and topoisomerase IV.

Formula: C₁₉H₂₂FN₃O₄

Purity: 99.50% - 99.85%

Color and Shape: White Powder

Molecular weight: 375.39

Ref: TM-T1293

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin

Purity: ≥98%

Molecular weight: 375.39g/mol

Ref: 54-BUP18589

Gatifloxacin

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Color and Shape: White To Off-White Solid

Molecular weight: 375.40

Ref: 4Z-G-344

Gatifloxacin

CAS: 112811-59-3

Formula: C₁₉H₂₂FN₃O₄

Color and Shape: Neat

Molecular weight: 375.39

Ref: 04-C13998600

1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

CAS: 112811-59-3

1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

Purity: 98%

Molecular weight: 375.39g/mol

Ref: 54-PC1528

Gatifloxacin

Controlled Product

CAS: 112811-59-3

Applications An antibacterial.
References Bauernfeind, A.: J. Antimicro. Chemother., 40, 639 (1997), Fukuda, H., et al.: Antimicrob. Ag. Chemother., 42, 1917 (1998),

Formula: C₁₉H₂₂FN₃O₄

Color and Shape: White To Off-White

Molecular weight: 375.39

Ref: TR-G250000

Gatifloxacin

CAS: 112811-59-3

Gatifloxacin is an antibiotic, which is a synthetic fluoroquinolone with broad-spectrum antibacterial activity. Its source lies in its chemical synthesis, designed to inhibit bacterial enzymes necessary for DNA replication. The mode of action involves the inhibition of bacterial DNA gyrase and topoisomerase IV, which are critical enzymes for bacterial DNA replication, transcription, and repair. This dual inhibitory mechanism disrupts bacterial cell division and growth, leading to the eventual eradication of susceptible bacterial strains.

Formula: C₁₉H₂₂FN₃O₄

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 375.39 g/mol

Ref: 3D-AC23649

Gatifloxacin - Bio-X ™

CAS: 112811-59-3

This product is part of our Bio-X ™ Range. These products are aimed at life science researchers who need high quality ready-to-use products for assay development, screening or other R&D work. With a solubility datasheet and convenient vials, all of our Bio-X ™ products are in stock across our global warehouses for rapid delivery and ease of use.

Formula: C₁₉H₂₂FN₃O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 375.39 g/mol

Ref: 3D-BG300001