CAS 1128181-21-4

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-(1-oxododecyl)-L-lysine

Description:

N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-(1-oxododecyl)-L-lysine, commonly referred to as Fmoc-Lys(1-oxododecyl)-OH, is a derivative of the amino acid lysine, modified for use in peptide synthesis and bioconjugation. This compound features a fluorenylmethoxycarbonyl (Fmoc) protecting group, which is widely used in solid-phase peptide synthesis due to its stability under basic conditions and ease of removal under acidic conditions. The presence of a dodecyl chain contributes to its hydrophobic characteristics, potentially influencing solubility and interaction with biological membranes. The oxo group at the dodecyl position may also participate in various chemical reactions, enhancing its utility in synthetic applications. Overall, this compound is characterized by its dual functionality, combining the properties of a protected amino acid with a hydrophobic tail, making it suitable for applications in drug delivery, peptide synthesis, and the development of biomaterials.

Formula: C₃₃H₄₆N₂O₅

InChI: InChI=1S/C33H46N2O5/c1-2-3-4-5-6-7-8-9-10-22-31(36)34-23-16-15-21-30(32(37)38)35-33(39)40-24-29-27-19-13-11-17-25(27)26-18-12-14-20-28(26)29/h11-14,17-20,29-30H,2-10,15-16,21-24H2,1H3,(H,34,36)(H,35,39)(H,37,38)/t30-/m0/s1

InChI key: InChIKey=UXJNSRCQVANCFJ-PMERELPUSA-N

SMILES: C(OC(N[C@@H](CCCCNC(CCCCCCCCCCC)=O)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• Fmoc-lys(dodecanoyl)-OH
• N2-[(9H-Fluoren-9-ylmethoxy)carbonyl]-N6-(1-oxododecyl)-L-lysine
• L-Lysine, N2-[(9H-fluoren-9-ylmethoxy)carbonyl]-N6-(1-oxododecyl)-

Fmoc-L-Lys(lauroyl)-OH

CAS: 1128181-21-4

used in the synthesis of modified peptides with increased lipophilicity.

Formula: C₃₃H₄₆N₂O₅

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 550.7 g/mol

Ref: 3D-DVB18121