CAS 112828-15-6: (R)-Naproxen Acyl-b-D-glucuronide

Description:(R)-Naproxen Acyl-β-D-glucuronide is a metabolite of the nonsteroidal anti-inflammatory drug (NSAID) naproxen, which is commonly used for its analgesic and anti-inflammatory properties. This compound is characterized by its glucuronide conjugation, which enhances its solubility and facilitates excretion from the body. The structure features a naproxen moiety linked to a β-D-glucuronic acid unit, resulting in a polar compound that is typically more water-soluble than its parent drug. This transformation is part of the phase II metabolic process, where drugs are conjugated to glucuronic acid to increase their elimination. The (R) configuration indicates the specific stereochemistry of the naproxen portion, which is important for its biological activity. As a metabolite, (R)-Naproxen Acyl-β-D-glucuronide may exhibit different pharmacokinetic and pharmacodynamic properties compared to naproxen itself, influencing its therapeutic effects and potential side effects. Understanding this compound is crucial for evaluating the metabolism and efficacy of naproxen in clinical settings.

Formula:C₂₀H₂₂O₉

InChI:InChI=1/C20H22O9/c1-9(10-3-4-12-8-13(27-2)6-5-11(12)7-10)19(26)29-20-16(23)14(21)15(22)17(28-20)18(24)25/h3-9,14-17,20-23H,1-2H3,(H,24,25)/t9-,14-,15-,16-,17?,20-/m1/s1

Synonyms:
(R)-Naproxen Acyl--D-glucuronide
(R)-Naproxen Glucuronide
1-[(aR)-6-Methoxy-a-methyl-2-naphthaleneacetate] -D-Glucopyranuronic Acid

Found 3 products.

Product data	Purity	Price range	Estimated delivery
(R)-Naproxen acyl-b-D-glucuronide REF: 7W-GC5773CAS: 112828-15-6	- - -	To inquire	Tue 04 Mar 25
(R)-Naproxen Acyl-Beta-D-glucuronide REF: TR-N377515CAS: 112828-15-6	- - -	216.00 €~1,617.00 €	Fri 11 Apr 25
(R)-Naproxen acyl-β-D-glucuronide REF: 3D-MN07306CAS: 112828-15-6	Min. 95%	645.00 €~3,615.00 €	Mon 14 Apr 25