CAS 112839-32-4

cis-Furconazole

Description:

Cis-Furconazole is a synthetic antifungal agent belonging to the class of imidazole derivatives. It is primarily used in the treatment of fungal infections, particularly those caused by dermatophytes and yeast. The compound exhibits a broad spectrum of antifungal activity by inhibiting the synthesis of ergosterol, an essential component of fungal cell membranes, thereby disrupting their integrity and function. Cis-Furconazole is characterized by its specific stereochemistry, which influences its biological activity and pharmacokinetic properties. It is typically administered topically or systemically, depending on the type and severity of the infection. The substance is known for its relatively low toxicity profile, making it suitable for various therapeutic applications. Additionally, its solubility and stability under physiological conditions contribute to its effectiveness as an antifungal agent. As with any pharmaceutical compound, the use of cis-Furconazole should be guided by clinical considerations and potential interactions with other medications.

Formula: C₁₅H₁₄Cl₂F₃N₃O₂

InChI: InChI=1/C15H14Cl2F3N3O2/c16-10-1-2-11(12(17)5-10)14(6-23-9-21-8-22-23)4-3-13(25-14)24-7-15(18,19)20/h1-2,5,8-9,13H,3-4,6-7H2/t13-,14+/s2

InChI key: InChIKey=ULCWZQJLFZEXCS-DUXBJXIBNA-N

SMILES: C([C@]1(O[C@@H](OCC(F)(F)F)CC1)C2=C(Cl)C=C(Cl)C=C2)N3C=NC=N3

Synonyms:

• 1-{[(2R,5R)-2-(2,4-dichlorophenyl)-5-(2,2,2-trifluoroethoxy)tetrahydrofuran-2-yl]methyl}-1H-1,2,4-triazole
• 1H-1,2,4-Triazole, 1-(((2R,5R)-2-(2,4-dichlorophenyl)tetrahydro-5-(2,2,2-trifluoroethoxy)-2-furanyl)methyl)-, rel-
• 1H-1,2,4-Triazole, 1-((2-(2,4-dichlorophenyl)tetrahydro-5-(2,2,2-trifluoroethoxy)-2-furanyl)methyl)-, cis-
• Brn 3571881
• Furconazole-cis
• Furconazole-cis [ISO]
• Ls 840606
• cis-Furconazole [ISO:BSI]
• rel-1-[[(2R,5R)-2-(2,4-Dichlorophenyl)tetrahydro-5-(2,2,2-trifluoroethoxy)-2-furanyl]methyl]-1H-1,2,4-triazole
• cis-Furconazole