CAS 112856-44-7

Losigamone

Description:

Losigamone is a chemical compound primarily recognized for its application in the field of neuroscience, particularly as an anticonvulsant agent. It is classified as a selective inhibitor of the enzyme phosphodiesterase, which plays a crucial role in the modulation of intracellular signaling pathways. This compound exhibits a unique mechanism of action that enhances the levels of cyclic nucleotides, thereby influencing neuronal excitability and synaptic transmission. Losigamone has been studied for its potential therapeutic effects in various neurological disorders, including epilepsy and other seizure-related conditions. Its pharmacological profile suggests a favorable safety and efficacy balance, although specific clinical outcomes may vary. The compound is typically administered in a controlled dosage to achieve the desired therapeutic effect while minimizing side effects. As with many pharmaceuticals, ongoing research continues to explore its full potential and mechanisms of action, contributing to a deeper understanding of its role in treating neurological disorders.

Formula: C₁₂H₁₁ClO₄

InChI: InChI=1/C12H11ClO4/c1-16-9-6-10(14)17-12(9)11(15)7-4-2-3-5-8(7)13/h2-6,11-12,15H,1H3/t11-,12-/s2

InChI key: InChIKey=ICDNYWJQGWNLFP-XXCBQWOANA-N

SMILES: [C@H](O)([C@]1(C(OC)=CC(=O)O1)[H])C2=C(Cl)C=CC=C2

Synonyms:

• 2(5H)-Furanone, 5-[(2-chlorophenyl)hydroxymethyl]-4-methoxy-, (R*,S*)-
• rel-(5S)-5-[(R)-(2-Chlorophenyl)hydroxymethyl]-4-methoxy-2(5H)-furanone
• Losigamona [INN-Spanish]
• Losigame
• 2(5H)-Furanone, 5-[(R)-(2-chlorophenyl)hydroxymethyl]-4-methoxy-, (5S)-rel-
• Losigamonum [INN-Latin]
• Losigamona
• 2(5H)-Furanone, 5-((2-chlorophenyl)hydroxymethyl)-4-methoxy-, (R*,S*)-
• Losigamonum
• (5R)-5-[(S)-(2-chlorophenyl)(hydroxy)methyl]-4-methoxyfuran-2(5H)-one
• UNII-84R8O3QM2G
• AO 33
• Losigamone
• Losigamone [INN]
• AO 33
• (R*,S*)-5-((2-Chlorophenyl)hydroxymethyl)-4-methoxy-2(5H)-furanone
• 5-[(2-chlorophenyl)(hydroxy)methyl]-4-methoxyfuran-2(5H)-one
• (5R*)-5-((alpha-S*)-o-Chloro-alpha-hydroxybenzyl)-4-methoxy-2(5H)-furanone

Losigamone

CAS: 112856-44-7

Losigamone

Purity: ≥98%

Molecular weight: 254.67g/mol

Ref: 54-BUP00914

Losigamone

CAS: 112856-44-7

Losigamone (AO-33) is an agonist of GABA receptor and can be used in studies about the treatment of partial seizures.

Formula: C₁₂H₁₁ClO₄

Purity: 99.98%

Color and Shape: Solid

Molecular weight: 254.67

Ref: TM-T27845