CAS 112859-71-9

Fluasterone

Description:

Fluasterone, identified by its CAS number 112859-71-9, is a synthetic steroid compound that belongs to the class of androgens. It is characterized by its structural modifications that enhance its anabolic properties while potentially minimizing androgenic effects. Fluasterone is often studied for its potential applications in muscle growth and performance enhancement, as well as its effects on metabolism. The compound exhibits a high affinity for androgen receptors, which plays a crucial role in mediating its biological effects. Additionally, Fluasterone may influence various physiological processes, including protein synthesis and nitrogen retention, making it of interest in both medical and athletic contexts. However, like many synthetic steroids, it may also carry risks of side effects and legal restrictions in sports. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile. As with any steroid, careful consideration of dosage and potential interactions with other substances is necessary for safe use.

Formula: C₁₉H₂₇FO

InChI: InChI=1S/C19H27FO/c1-18-9-4-3-5-12(18)6-7-13-14(18)8-10-19(2)15(13)11-16(20)17(19)21/h6,13-16H,3-5,7-11H2,1-2H3/t13-,14+,15+,16-,18+,19+/m1/s1

InChI key: InChIKey=VHZXNQKVFDBFIK-NBBHSKLNSA-N

SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)C(=CC3)CCCC4)(CC1)[H])[H])(C[C@@H](F)C2=O)[H]

Synonyms:

• (16Alpha)-16-Fluoroandrost-5-En-17-One
• (16α)-16-Fluoroandrost-5-en-17-one
• (8R,9S,10R,13S,14S)-16-fluoro-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one
• 16alpha-Fluoro-5-androsten-17-one
• 16α-Fluoro-5-androsten-17-one
• Androst-5-en-17-one, 16-fluoro-, (16alpha)-
• Androst-5-en-17-one, 16-fluoro-, (16α)-
• Ccris 4216
• Fluasterone

Fluasterone

Controlled Product

CAS: 112859-71-9

Applications A synthetic derivative of Dehydroepiandrosterone. The reduced androgenicity of Fluasterone may obviate toxicities associated with the androgenicity of the parent compound. Antitumor agent. Used in clinical trials for prostate cancer prevention.
References Bentley, P., et al.: Food Chem. Toxicol., 31, 857 (1993), Rao, K., et al.: Cancer Res., 59, 3084 (1999), Masuzaki, H., et al.: Science, 294, 2166 (2001), Osawa, E., et al.: Life Sci., 70, 2623 (2002),

Formula: C₁₉H₂₇FO

Color and Shape: White To Off-White

Molecular weight: 290.42

Ref: TR-F500300

Fluasterone

Controlled Product

CAS: 112859-71-9

Fluasterone is a synthetic, nonsteroidal compound that belongs to the class of selective androgen receptor modulators (SARMs). It has been shown to have anti-inflammatory properties as well as anabolic effects. Fluasterone is also able to bind to and activate the CB2 receptor. This drug has been shown to be effective in animal models for inflammatory bowel disease and skin tumor formation. Fluasterone has also been found to be metabolized by cytochrome P450 2C8 (CYP2C8) and CYP3A4 enzymes, which may lead to metabolic disorders such as diabetes mellitus and hypercholesterolemia. The drug has low potency due to its inability to bind effectively with the androgen receptor in target tissues.

Formula: C₁₉H₂₇FO

Purity: Min. 95%

Molecular weight: 290.42 g/mol

Ref: 3D-FF23313

Fluasterone

CAS: 112859-71-9

Fluasterone, an NF-κB activation inhibitor, is used potentially for the treatment of metabolic syndrome.

Formula: C₁₉H₂₇FO

Purity: 98%

Color and Shape: Solid

Molecular weight: 290.42

Ref: TM-T27338