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CAS 112883-29-1

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Fmoc-D-Tyr-OH

Description:
Fmoc-D-Tyr-OH, or 9-fluorenylmethoxycarbonyl-D-tyrosine, is a protected form of the amino acid D-tyrosine, commonly used in peptide synthesis. The Fmoc group serves as a protective moiety that allows for selective deprotection during the synthesis process. This compound features a phenolic hydroxyl group, which is characteristic of tyrosine, contributing to its reactivity and potential for further modifications. Fmoc-D-Tyr-OH is typically white to off-white in appearance and is soluble in organic solvents such as dimethylformamide (DMF) and dimethyl sulfoxide (DMSO), but less soluble in water. Its molecular structure includes a fluorenyl ring, which provides stability and aids in the purification of peptides. The compound is widely utilized in solid-phase peptide synthesis due to its ease of handling and compatibility with various coupling reagents. As with many amino acid derivatives, it is important to handle Fmoc-D-Tyr-OH with care, following appropriate safety protocols, as it may pose health risks if ingested or inhaled.
Formula:C24H21NO5
InChI:InChI=1/C24H21NO5/c26-16-11-9-15(10-12-16)13-22(23(27)28)25-24(29)30-14-21-19-7-3-1-5-17(19)18-6-2-4-8-20(18)21/h1-12,21-22,26H,13-14H2,(H,25,29)(H,27,28)/t22-/m1/s1
SMILES:c1ccc2c(c1)c1ccccc1C2COC(=N[C@H](Cc1ccc(cc1)O)C(=O)O)O
Synonyms:
  • Fmoc-D-tyrosine
  • N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-tyrosine
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