CAS 112883-40-6

D-FMOC-methionine

Description:

D-FMOC-methionine, with the CAS number 112883-40-6, is a derivative of the amino acid methionine, which is essential for protein synthesis and plays a critical role in various biological processes. The "D-FMOC" designation indicates that this compound is a D-enantiomer of methionine that has been protected with a 9-fluorenylmethoxycarbonyl (FMOC) group, a common protective group used in peptide synthesis to prevent unwanted reactions at the amino group. This modification enhances the stability and solubility of the amino acid during chemical reactions. D-FMOC-methionine is typically utilized in solid-phase peptide synthesis, allowing for the selective coupling of amino acids in a controlled manner. Its characteristics include a relatively high molecular weight compared to unmodified methionine, and it is generally soluble in organic solvents. The compound is important in the field of biochemistry and pharmaceutical research, particularly in the synthesis of peptides and proteins with specific structural and functional properties.

Formula: C₂₀H₂₁NO₄S

InChI: InChI=1S/C20H21NO4S/c1-26-11-10-18(19(22)23)21-20(24)25-12-17-15-8-4-2-6-13(15)14-7-3-5-9-16(14)17/h2-9,17-18H,10-12H2,1H3,(H,21,24)(H,22,23)/t18-/m1/s1

InChI key: InChIKey=BUBGAUHBELNDEW-GOSISDBHSA-N

SMILES: C(OC(N[C@H](CCSC)C(O)=O)=O)C1C=2C(C=3C1=CC=CC3)=CC=CC2

Synonyms:

• (2R)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-4-methylsulfanylbutanoic acid
• (2R)-2-([[(9H-Fluoren-9-yl)methoxy]carbonyl]amino)-4-(methylsulfanyl)butanoic acid
• 291: PN: US20070042401 PAGE: 37 claimed protein
• 9-Fluorenylmethoxycarbonyl-D-Methionine
• 982: PN: WO2006135786 PAGE: 70 claimed protein
• <span class="text-smallcaps">D</span>-FMOC-methionine
• <span class="text-smallcaps">D</span>-Methionine, N-[(9H-fluoren-9-ylmethoxy)carbonyl]-
• Fmoc-D-Met
• Fmoc-D-Met-OH
• N-(9-Fluorenylmethoxycarbonyl)-<span class="text-smallcaps">D</span>-methionine
• N-(9-Fluorenylmethoxycarbonyl)-D-Methionine
• N-Alpha-(9-Fluorenylmethoxycarbonyl)-D-Methionine
• N-Alpha-(9-Fluorenylmethyloxycarbonyl)-D-Methionine
• N-Alpha-Fmoc-D-Methionine
• N-Fmoc-D-Methionine
• N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-<span class="text-smallcaps">D</span>-methionine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]-D-methionine
• N-[(9H-fluoren-9-ylmethoxy)carbonyl]methionine
• NALPHA-9-Fluorenylmethoxycarbonyl-D-methionine

N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-D-methionine

CAS: 112883-40-6

Formula: C₂₀H₂₁NO₄S

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 371.45

Ref: 3B-F0594

Fmoc-D-Met-OH

CAS: 112883-40-6

Bachem ID: 4004745.

Formula: C₂₀H₂₁NO₄S

Purity: > 99%

Color and Shape: White

Molecular weight: 371.46

Ref: 01-4004745

Fmoc-D-Met-OH

CAS: 112883-40-6

Formula: C₂₀H₂₁NO₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 371.4500

Ref: IN-DA0078PW

Fmoc-D-Met-OH

CAS: 112883-40-6

Fmoc-D-Met-OH

Formula: C₂₀H₂₁NO₄S

Purity: 98%

Color and Shape: white solid

Molecular weight: 371.45g/mol

Ref: 54-OR911613

D-Methionine-d3-N-FMOC(S-methyl-d3)

CAS: 112883-40-6

Formula: CD₃SCH₂CH₂CH(NHFMOC)COOH

Purity: 98 atom % D

Color and Shape: White Solid

Molecular weight: 374.47

Ref: 3U-D6624

Fmoc-D-Met-OH

CAS: 112883-40-6

Fmoc-D-Met-OH is a useful organic compound for research related to life sciences. The catalog number is T67557 and the CAS number is 112883-40-6.

Formula: C₂₀H₂₁NO₄S

Color and Shape: Solid

Molecular weight: 371.45

Ref: TM-T67557

N-Fmoc-D-Methionine (Fmoc-D-Met-OH)

CAS: 112883-40-6

Formula: C₂₀H₂₁NO₄S

Molecular weight: 371.45

Ref: 4Z-M-4726

Fmoc-D-Met-OH

CAS: 112883-40-6

M03369 - Fmoc-D-Met-OH

Formula: C₂₀H₂₁NO₄S

Purity: 95%

Color and Shape: Solid

Molecular weight: 371.45

Ref: 10-M03369

FMOC-D-Methionine extrapure, 99%

CAS: 112883-40-6

Formula: C₂₀H₂₁NO₄S

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 371.46

Ref: SR-23694

N-Fmoc-D-methionine

Controlled Product

CAS: 112883-40-6

Applications N-Fmoc-D-methionine is an N-Fmoc-protected form of D-Methionine (M260550). D-Methionine is an isomer of L-Methionine (M260440), and is known to be a cytoprotectant against Cisplatin (C499500), an anticancer agent. D-Methionine is also used to prevent noise- and drug-induced hearing loss, as well as hair loss (all of which may also be caused by Cisplatin or aminoglycosides).
References Campbell, K., et al.: Hear. Res., 92, 103 (2007); Cloven, N., et al.: Antican. Res., 20.6B, 4205 (1999); Vuyyuri, S., et al.: Clin. Cancer Res., 14, 2161 (2008)

Formula: C₂₀H₂₁NO₄S

Color and Shape: Neat

Molecular weight: 371.45

Ref: TR-F622850