CAS 112885-42-4

Mosapride citrate

Description:

Mosapride citrate is a medication primarily used as a gastroprokinetic agent, which means it enhances gastrointestinal motility. It is often prescribed for the treatment of functional dyspepsia and gastroesophageal reflux disease (GERD). The substance acts as a selective serotonin 5-HT4 receptor agonist, promoting the release of acetylcholine in the gastrointestinal tract, thereby facilitating peristalsis and improving gastric emptying. Mosapride citrate is typically administered in its citrate salt form, which enhances its solubility and bioavailability. The compound is characterized by its relatively low toxicity and favorable safety profile, making it suitable for long-term use in patients with digestive disorders. In terms of physical properties, it is generally a white to off-white crystalline powder, soluble in water, and stable under normal storage conditions. Its pharmacokinetics involve rapid absorption and a moderate half-life, allowing for effective dosing regimens. Overall, Mosapride citrate is an important therapeutic agent in the management of gastrointestinal motility disorders.

Formula: C₂₁H₂₅ClFN₃O₃·C₆H₈O₇

InChI: InChI=1S/C21H25ClFN3O3.C6H8O7/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12)

InChI key: InChIKey=HUZTYZBFZKRPFG-UHFFFAOYSA-N

SMILES: C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)(=O)C3=C(OCC)C=C(N)C(Cl)=C3.C(CC(O)=O)(CC(O)=O)(C(O)=O)O

Synonyms:

• (+-)-4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)B
• 4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide 2-hydroxypropane-1,2,3-tricarboxylate dihydrate (salt)
• As 4370
• As4370
• Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1)
• Benzamide,4-Amino-5-Chloro-2-Ethoxy-N-((4-((4-Fluorophenyl)Methyl)-2-Morpholin
• Enzamidecitrate
• Gasmotin
• Mosid MT
• Yl)Methyl)-,2-Hydroxy-1,2,3-Propanetricarboxylate(1:1)

Mosapride Citrate

CAS: 112885-42-4

Formula: C₂₁H₂₅ClFN₃O₃·C₆H₈O₇

Color and Shape: White To Off-White Solid

Molecular weight: 421.90 192.12

Ref: 4Z-M-542

Mosapride citrate

CAS: 112885-42-4

Formula: C₂₇H₃₇ClFN₃O₁₂

Purity: 98.0 - 101.5 % (dry basis)

Color and Shape: White to off-white crystalline powder

Molecular weight: 650.05

Ref: 7W-GP1855

Mosapride Citrate

CAS: 112885-42-4

Mosapride Citrate

Purity: ≥98%

Molecular weight: 614.02g/mol

Ref: 54-BUP15673

Mosapride Citrate

CAS: 112885-42-4

Mosapride Citrate

Purity: 99%

Molecular weight: 614.02g/mol

Ref: 54-PC109125

Mosapride Citrate

CAS: 112885-42-4

Mosapride Citrate (TAK-370 citrate), a gastroprokinetic agent, utilizes as a selective 5HT4 agonist.

Formula: C₂₁H₂₅ClFN₃O₃·C₆H₈O₇

Purity: 99.70%

Color and Shape: White Powder

Molecular weight: 614.02

Ref: TM-T6597

Mosapride citrate

CAS: 112885-42-4

Serotonin 5-HT4 receptor agonist

Formula: C₂₇H₂₅ClFN₃O₃•C₆H₈O₇

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 614.02 g/mol

Ref: 3D-FM32515

Mosapride citrate - Bio-X ™

CAS: 112885-42-4

Mosapride is a prokinetic 5-HT4 receptor agonist used to increase colon and gastric mobility. This drug allows the release of acetylcholine from enteric cholinergic neurons. Mosapride has also shown to provide relief when treating patients with constipation- type irritable bowel syndrome as it prevents abdominal pain.

Formula: C₂₇H₃₃ClFN₃O₁₀

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 614.02 g/mol

Ref: 3D-BM164611