CAS 112955-31-4

ALA-VAL-SER-GLU-HIS-GLN-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-NH2

Description:

The chemical substance with the name "ALA-VAL-SER-GLU-HIS-GLN-LEU-LEU-HIS-ASP-LYS-GLY-LYS-SER-ILE-GLN-ASP-LEU-ARG-ARG-ARG-PHE-PHE-LEU-HIS-HIS-LEU-ILE-ALA-GLU-ILE-HIS-THR-ALA-NH2" and CAS number "112955-31-4" is a peptide composed of a sequence of amino acids. This peptide features a diverse array of amino acids, including both hydrophobic and hydrophilic residues, which contribute to its structural and functional properties. The presence of multiple histidine and arginine residues suggests potential roles in metal ion binding and biological activity, while the terminal amine group (NH2) indicates that it is a peptide amide. Such peptides can exhibit various biological activities, including enzyme regulation, signaling, and potential therapeutic effects. The specific sequence of amino acids influences the peptide's conformation, stability, and interactions with other biomolecules, making it a subject of interest in fields such as biochemistry, pharmacology, and molecular biology.

Formula: C₁₈₀H₂₈₈N₅₈O₄₇

Synonyms:

• Pth-Rp (Human, 1-34 Amide) (Rat, Mouse)
• Parathyroid Hormone Related Protein (Human, 1-34 Amide) (Rat, Mouse)
• Hypercalcemia Of Malignancy Factor*Fragm Ent 1-34 Am
• Parathyroid hormone-related protein (1-34) Amide, PTHrP (1-34) amide, Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-NH2

pTH-Related Protein (1-34) amide (human, mouse, rat)

CAS: 112955-31-4

Bachem ID: 4031196.

Formula: C₁₈₀H₂₈₈N₅₈O₄₇

Purity: 91.3%

Color and Shape: White Lyophilisate

Molecular weight: 4016.63

Ref: 01-4031196

PTH-rP (Human,1-34 Amide)

CAS: 112955-31-4

PTH-rP is a peptide that has been used as a research tool for the study of ion channels, protein interactions, and receptor signaling. It is an inhibitor of PTH/PTH-related protein receptor. PTH-rP is a ligand for the PTH/PTH-related protein receptor and can be used to identify novel receptors or ligands. This compound has been shown to have the ability to inhibit cellular proliferation and induce apoptosis in certain cell lines.

Formula: C₁₈₀H₂₈₈N₅₈O₄₇

Purity: Min. 95%

Molecular weight: 4,016.6 g/mol

Ref: 3D-PTH-4205-V

pTH-Related Protein (1-34) amide (human, mouse, rat) trifluoroacetate salt

CAS: 112955-31-4

Parathyroid hormone-related protein (PTHrP) is a peptide hormone produced by the parathyroid gland that functions as a phosphatase, inhibiting alkaline phosphatase. It also has an inhibitory effect on osteoclastic bone resorption and stimulates osteoblastic bone formation. PTHrP has been shown to be useful in treating osteoporosis and Paget's disease. It also has been used in conjunction with dexamethasone to treat patients with malignancies of the head and neck. PTHrP is an inhibitor of protein kinase A and phosphodiesterases, which are enzymes that regulate cellular processes such as proliferation and differentiation.

Formula: C₁₈₀H₂₈₈N₅₈O₄₇

Purity: Min. 95%

Molecular weight: 4,016.58 g/mol

Ref: 3D-FP110380