CAS 112981-69-8

3,5-Bis(trifluoromethyl)phenylmagnesium bromide

Description:

3,5-Bis(trifluoromethyl)phenylmagnesium bromide is an organomagnesium compound, specifically a Grignard reagent, characterized by its highly reactive nature due to the presence of the magnesium-bromine bond. This compound features a phenyl ring substituted at the 3 and 5 positions with trifluoromethyl groups, which significantly enhance its electrophilic character. The trifluoromethyl groups are known for their strong electron-withdrawing properties, which can influence the reactivity of the phenyl ring in nucleophilic substitution reactions. As a Grignard reagent, it is typically used in organic synthesis for the formation of carbon-carbon bonds, allowing for the introduction of the 3,5-bis(trifluoromethyl)phenyl group into various organic molecules. The compound is sensitive to moisture and air, requiring an anhydrous environment for storage and handling. Its reactivity can lead to the formation of various derivatives, making it a valuable intermediate in the synthesis of fluorinated compounds and pharmaceuticals. Proper safety precautions should be taken due to its reactivity and potential hazards associated with handling organometallic compounds.

Formula: C₈H₃BrF₆Mg

InChI: InChI=1/C8H3F6.BrH.Mg/c9-7(10,11)5-2-1-3-6(4-5)8(12,13)14;;/h2-4H;1H;/q-1;;+2/p-1

SMILES: C1=CC(=C[C-](C=1)C(F)(F)F)C(F)(F)F.Br.[Mg]

Synonyms:

• Magnesium Bromide 3,5-Bis(Trifluoromethyl)Benzenide (1:1:1)
• 3,5-Bis(trifluoromethyl)phenylmagnesium bromide 0.5M in tetrahydrofuran
• 3,5-Bis(trifluoroMethyl)phenylMagnesiuM broMide, 0.5 M solution in THF, SpcSeal
• 3,5-bis(trifluoromethyl)phenylmagnesium bromide solution
• 3,5-Bis(trifluoromethyl)phenylmagnesium bromide, 0.5M solution in THF, AcroSeal
• (3 5 BIS(TRIFLUOROMETHYL)PHENYL)MAGNESI&
• 3,5-BIS(TRIFLUOROMETHYL)PHENYLMAGNESIUM BROMIDE, 0,5M SOLUTION IN THF
• 3,5-Bis(trifluoroMethyl)phenylMagnesiuM broMide, 0.5 M solution in THF, J&KSeal
• 3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution 0.5 M in THF
• 3,5-Bis(trifluoromethyl)phenylmagnesium bromide, 0.5M solution in THF, AcroSeal§3
• 3,5-Bis(trifluoromethyl)phenylmagnesium bromide solution 0.5 in THF