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CAS 113-07-5

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Doxapram hydrochloride

Description:
Doxapram hydrochloride is a synthetic compound primarily used as a respiratory stimulant in clinical settings. It is classified as a central nervous system stimulant and is often administered to treat conditions such as respiratory depression, particularly in patients recovering from anesthesia or those with chronic obstructive pulmonary disease (COPD). The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration via intravenous or intramuscular routes. Doxapram acts by stimulating the chemoreceptors in the carotid body, leading to increased respiratory drive and improved oxygenation. Its pharmacological effects include increased tidal volume and respiratory rate, making it beneficial in acute respiratory failure scenarios. However, it is essential to monitor patients closely for potential side effects, which may include hypertension, tachycardia, and nervousness. As with any medication, the use of doxapram hydrochloride should be guided by a healthcare professional, considering the patient's specific medical condition and history.
Formula:C24H30N2O2·ClH
InChI:InChI=1S/C24H30N2O2.ClH/c1-2-26-19-22(13-14-25-15-17-28-18-16-25)24(23(26)27,20-9-5-3-6-10-20)21-11-7-4-8-12-21;/h3-12,22H,2,13-19H2,1H3;1H
InChI key:InChIKey=MBGXILHMHYLZJT-UHFFFAOYSA-N
SMILES:C(CN1CCOCC1)C2C(C(=O)N(CC)C2)(C3=CC=CC=C3)C4=CC=CC=C4.Cl
Synonyms:
  • 1-Ethyl-4-(2-Morpholinoethyl)-3,3-Diphenylpyrrolidin-2-One Monohydrochloride
  • 1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidinone hydrochloride
  • 1-Ethyl-4-[2-(Morpholin-4-Yl)Ethyl]-3,3-Diphenylpyrrolidin-2-One Hydrochloride (1:1)
  • 2-Pyrrolidinone, 1-ethyl-4-(2-(4-morpholinyl)ethyl)-3,3-diphenyl-, monohydrochloride
  • 2-Pyrrolidinone, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-, hydrochloride
  • 2-Pyrrolidinone, 1-ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-, monohydrochloride
  • 2-Pyrrolidinone, 1-ethyl-4-[2-(4-morpholinyl)ethyl]-3,3-diphenyl-, hydrochloride (1:1)
  • 3,3-Diphenyl-1-ethyl-4-(2-morpholinoethyl)-2-pyrrolidinone hydrochloride
  • Dopram
  • Dothiepinhydrochloride,Anhydrous
  • See more synonyms
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