CAS 113-18-8

Ethchlorvynol

Description:

Ethchlorvynol, with the CAS number 113-18-8, is a synthetic compound primarily used as a sedative and hypnotic agent. It is classified as a chlorinated derivative of vinyl alcohol and is known for its sedative properties, making it effective in treating insomnia and anxiety. Ethchlorvynol appears as a white to off-white crystalline powder and is typically administered orally. The compound is soluble in organic solvents but has limited solubility in water. Its mechanism of action involves enhancing the effects of gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission in the central nervous system. While it has therapeutic applications, ethchlorvynol can also lead to dependence and has potential for abuse, necessitating careful monitoring when prescribed. Side effects may include drowsiness, dizziness, and gastrointestinal disturbances. Due to safety concerns and the availability of newer sedative agents, its clinical use has diminished over time.

Formula: C₇H₉ClO

InChI: InChI=1S/C7H9ClO/c1-3-7(9,4-2)5-6-8/h1,5-6,9H,4H2,2H3

InChI key: InChIKey=ZEHYJZXQEQOSON-UHFFFAOYSA-N

SMILES: C(C=CCl)(CC)(C#C)O

Synonyms:

• 1-Chloro-3-ethyl-1-penten-4-yn-3-ol
• 3-(β-Chlorvinyl)-1-pentyn-3-ol
• Alvinol
• Arvynol
• Ethchlorovynol
• Ethchlorvinol
• Ethchlorvynol
• Ethclorvynol
• Ethochlorvynol
• Ethyl β-chlorovinyl ethynyl carbinol
• Ethyl-2-chlorovinyl ethynyl carbinol
• Normoson
• Nostel
• Nsc 30372
• Placidyl
• Roeridorm
• Serenesil
• Serensil
• (1Z)-1-chloro-3-ethylpent-1-en-4-yn-3-ol
• 1-chloro-3-ethylpent-1-en-4-yn-3-ol
• (1E)-1-chloro-3-ethylpent-1-en-4-yn-3-ol

Ethchlorvynol

Controlled Product

CAS: 113-18-8

Applications Controlled substance (depressant). Sedative; hypnotic.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Horwitz, et al.: Drug Metab. Dispos., 8, 77 (1980),

Formula: C₇H₉ClO

Color and Shape: Neat

Molecular weight: 144.60

Ref: TR-E677000

Ethchlorvynol

Controlled Product

CAS: 113-18-8

Ethchlorvynol is a sedative, hypnotic, and anticonvulsant drug that is used to treat insomnia. It has been shown to cause cell lysis in tissue culture and decreases the levels of ATP in the cells. Ethchlorvynol also causes hyperpolarization of the cell membrane and inhibits the activity of p-450 enzymes. The clinical response to ethchlorvynol has been shown to be related to its ability to induce pleural fluid accumulation, leading to clinical pathology changes in patients with untreated tuberculosis. This drug can be detected by chromatographic methods or by biocompatible polymer methods, such as enzyme-linked immunosorbent assay (ELISA).

Formula: C₇H₉ClO

Purity: Min. 95%

Molecular weight: 144.6 g/mol

Ref: 3D-FE22854

Ethchlorvynol CIV

Controlled Product

CAS: 113-18-8

Ethchlorovynol (inn)

Formula: C₇H₉ClO

Color and Shape: Liquid

Molecular weight: 144.03419

Ref: 45-1258305