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CAS 113-52-0

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Imipramine HCl

Description:
Imipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of major depressive disorder and certain anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly norepinephrine and serotonin, thereby increasing their availability in the synaptic cleft. This mechanism contributes to its antidepressant effects. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Imipramine hydrochloride has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include dry mouth, sedation, weight gain, and potential cardiovascular effects, necessitating careful monitoring, especially in patients with pre-existing conditions. Due to its pharmacological profile, it is classified as a prescription medication and should be used under medical supervision. Additionally, it is important to consider potential interactions with other medications, as well as the risk of withdrawal symptoms upon discontinuation. Overall, Imipramine hydrochloride remains a significant option in the pharmacotherapy of depression and related disorders.
Formula:C19H25ClN2
InChI:InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H
InChI key:InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:
  • 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
  • 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
  • 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
  • 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
  • 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
  • Apo-Imipramine
  • Censtim
  • Censtin
  • See more synonyms
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Found 24 products.
  • Imipramine Hydrochloride

    CAS:
    Formula:C19H24N2·HCl
    Purity:>98.0%(HPLC)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:316.87

    Ref: 3B-I0971

    1g
    50.00€
    5g
    163.00€
  • Imipramine hydrochloride

    CAS:
    <p>A serotonin uptake inhibitor</p>
    Formula:C19H25ClN2
    Color and Shape:White to off White Powder
    Molecular weight:316.87

    Ref: 02-J63723

    5g
    68.00€
    25g
    209.00€
  • Imipramine Hydrochloride

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR0077.00

    10mg
    264.00€
  • Ref: LP-IMP-1066-HC-1LM

    1ml
    48.00€
  • Imipramine.HCl

    CAS:
    Color and Shape:Neat

    Ref: LP-IMP-1066-HC-10

    10mg
    89.00€
    50mg
    194.00€
    100mg
    317.00€
  • Ref: 61-AMP0077.00-01

    1ml
    87.00€
  • Imipramine hydrochloride

    CAS:
    Imipramine hydrochloride
    Formula:C19H25ClN2
    Purity:99.5%
    Color and Shape:Off White
    Molecular weight:316.17063

    Ref: 47-932

    100mg
    211.00€
  • IMIPRAMINE FOR SYSTEM SUITABILITY CRS

    CAS:
    <p>IMIPRAMINE FOR SYSTEM SUITABILITY CRS</p>
    Formula:C19H25ClN2
    Molecular weight:316.8682

    Ref: 41-Y0000893

    10mg
    115.00€
  • IMIPRAMINE HYDROCHLORIDE CRS

    CAS:
    <p>IMIPRAMINE HYDROCHLORIDE CRS</p>
    Formula:C19H25ClN2
    Color and Shape:Crystalline Powder. White. Light Yellow. Powder.
    Molecular weight:316.8682

    Ref: 41-I0100000

    50mg
    115.00€
  • Imipramine Hydrochloride

    CAS:
    <p>Clozapine; droperidol; and imipramine hydrochlorid</p>
    Formula:C19H24N2·ClH
    Color and Shape:White Powder
    Molecular weight:316.17063
  • Imipramine Hydrochloride

    CAS:
    Formula:C19H25ClN2
    Purity:95%
    Color and Shape:Solid
    Molecular weight:316.8682

    Ref: IN-DA0081OM

    1g
    98.00€
    5g
    271.00€
    100mg
    35.00€
    250mg
    51.00€
  • Imipramine HCl (Clomipramine HCl EP Impurity B HCl)

    CAS:
    Formula:C19H24N2·HCl
    Molecular weight:280.42 36.46

    Ref: 4Z-I-016

    5mg
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    10mg
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    25mg
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    50mg
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    100mg
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  • Imipramine hydrochloride

    CAS:
    <p>Imipramine hydrochloride</p>
    Purity:≥98%
    Molecular weight:316.87g/mol

    Ref: 54-BUP16484

    25mg
    52.00€
    50mg
    62.00€
    100mg
    85.00€
    500mg
    174.00€
  • Imipramine hydrochloride

    CAS:
    Formula:C19H24N2·HCl
    Purity:≥ 98.0%
    Color and Shape:White to almost white powder to crystal
    Molecular weight:316.87

    Ref: 7W-GP6668

    ne
    To inquire
  • Imipramine Hydrochloride

    CAS:
    Imipramine Hydrochloride
    Purity:98%
    Molecular weight:316.87g/mol

    Ref: 54-OR1029247

    1g
    61.00€
    5g
    189.00€
    25g
    828.00€
    250mg
    32.00€
  • Imipramine hydrochloride

    CAS:
    Formula:C19H24N2·ClH
    Color and Shape:Neat
    Molecular weight:316.87

    Ref: 04-C14285950

    50mg
    119.00€
  • Imipramine Hydrochloride

    CAS:
    Color and Shape:Off White

    Ref: 86-MM0077.00

    250mg
    869.00€
  • Imipramine hydrochloride

    CAS:
    <p>Imipramine HCl: 1st-gen tricyclic antidepressant, inhibits serotonin and norepinephrine uptake, blocks aSMase, reduces MV/exosome secretion.</p>
    Formula:C19H25ClN2
    Purity:99.65% - 99.98%
    Color and Shape:White To Off-White /Hydrochloride/ Un 1230 3/Pg 2
    Molecular weight:316.87
  • Imipramine Hydrochloride RS

    CAS:
    Color and Shape:White To Pale Yellow

    Ref: 2K-1016000021

    200mg
    To inquire
  • Imipramine hydrochloride

    CAS:
    Purity:95.0%
    Molecular weight:316.8699951171875

    Ref: 10-F053930

    1g
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    5g
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    25g
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  • Imipramine Hydrochloride

    CAS:
    <p>Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.<br>References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),<br></p>
    Formula:C19H24N2·ClH
    Color and Shape:Off White
    Molecular weight:316.87

    Ref: TR-I465980

    1g
    93.00€
    5g
    236.00€
    10g
    282.00€
  • Clomipramine EP Impurity B

    CAS:
    Formula:C19H24N2HCl
    Molecular weight:280.4 : 36.5

    Ref: ST-EA-CP-C30002

    10mg
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    25mg
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    50mg
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    100mg
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  • Imipramine HCl - Bio-X ™

    Controlled Product
    CAS:
    <p>Imipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.</p>
    Formula:C19H24N2•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:316.87 g/mol

    Ref: 3D-BI164574

    100mg
    134.00€
  • Imipramine hydrochloride

    Controlled Product
    CAS:
    <p>Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.</p>
    Formula:C19H25ClN2
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:316.87 g/mol

    Ref: 3D-FI24561

    2g
    204.00€
    5g
    341.00€
    10g
    478.00€
    25g
    668.00€
    100g
    920.00€