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CAS 113-52-0

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Imipramine HCl

Description:
Imipramine hydrochloride is a tricyclic antidepressant primarily used in the treatment of major depressive disorder and certain anxiety disorders. It functions by inhibiting the reuptake of neurotransmitters, particularly norepinephrine and serotonin, thereby increasing their availability in the synaptic cleft. This mechanism contributes to its antidepressant effects. The substance appears as a white to off-white crystalline powder and is soluble in water, which facilitates its administration in clinical settings. Imipramine hydrochloride has a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include dry mouth, sedation, weight gain, and potential cardiovascular effects, necessitating careful monitoring, especially in patients with pre-existing conditions. Due to its pharmacological profile, it is classified as a prescription medication and should be used under medical supervision. Additionally, it is important to consider potential interactions with other medications, as well as the risk of withdrawal symptoms upon discontinuation. Overall, Imipramine hydrochloride remains a significant option in the pharmacotherapy of depression and related disorders.
Formula:C19H25ClN2
InChI:InChI=1/C20H25N.ClH/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20;/h3-6,8-11,20H,7,12-15H2,1-2H3;1H
InChI key:InChIKey=XZZXIYZZBJDEEP-UHFFFAOYSA-N
SMILES:C(CCN(C)C)N1C=2C(CCC=3C1=CC=CC3)=CC=CC2.Cl
Synonyms:
  • 3-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)-N,N-dimethylpropan-1-aminium chloride
  • 3-(10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)-N,N-dimethylpropan-1-amine hydrochloride (1:1)
  • 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepin hydrochloride
  • 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
  • 5H-Dibenz[b,f]azepine, 5-[3-(dimethylamino)propyl]-10,11-dihydro-, monohydrochloride
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, hydrochloride (1:1)
  • 5H-Dibenz[b,f]azepine-5-propanamine, 10,11-dihydro-N,N-dimethyl-, monohydrochloride
  • Apo-Imipramine
  • Censtim
  • Censtin
  • See more synonyms
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products per page.Found 24 products.
  • Imipramine Hydrochloride
    TRC
    + Info

    Imipramine Hydrochloride

    CAS:
    <p>Applications Tricyclic antidepressant; inhibits the serotonin and norepinephrine transporters. Has little effect on the dopamine transporter.<br>References Wood, M.D., et al.: Neuropharmacology, 26, 1081 (1987), Casis, O., et al.: J. Cardiovasc. Pharmacol., 32, 521 (1998), Linner, L., et al.: Biol. Psychiatry, 46, 766 (1999), Teschemacher, et al.: Br. J. Pharmacol., 128, 479 (1999),<br></p>
    Formula:C19H24N2·ClH
    Color and Shape:Off White
    Molecular weight:316.87

    Ref: TR-I465980

    1g
    93.00€
    5g
    236.00€
    10g
    282.00€
  • Clomipramine EP Impurity B
    Standalix
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    Clomipramine EP Impurity B

    CAS:
    Formula:C19H24N2HCl
    Molecular weight:280.4 : 36.5

    Ref: ST-EA-CP-C30002

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  • Imipramine HCl - Bio-X ™
    Biosynth
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    Imipramine HCl - Bio-X ™

    Controlled Product
    CAS:
    <p>Imipramine is a drug that belongs to the class of tricyclic antidepressant drugs. It is used in the treatment of depression and childhood enuresis. It is a potent inhibitor of serotonin and norepinephrine reuptake. Imipramine blocks D-2 receptors, H1 receptors, α-1 and α-2 adrenergic receptors and muscarinic receptors. Also, it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.</p>
    Formula:C19H24N2•HCl
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:316.87 g/mol

    Ref: 3D-BI164574

    100mg
    134.00€
  • Imipramine hydrochloride
    Biosynth
    + Info

    Imipramine hydrochloride

    Controlled Product
    CAS:
    <p>Imipramine hydrochloride is a hydrochloride salt form of imipramine, a surface active tricyclic drug, a potent inhibitor of serotonin and norepinephrine reuptake. It has a greater affinity for the serotonin and it has more anticholinergic side effects which can be helpful in treating enuresis. Imipramine blocks D-2 receptors, H1 receptors, alpha 1 and alpha 2 adrenergic receptors and muscarinic receptors. It is used for therapy of depression (major and bipolar) and nocturnal enuresis in children. Also it is indicated for dysthymia, attention-deficit disorders, agoraphobia and it is effective in treating anxiety and panic disorders.</p>
    Formula:C19H25ClN2
    Purity:Min. 95%
    Color and Shape:Powder
    Molecular weight:316.87 g/mol

    Ref: 3D-FI24561

    2g
    204.00€
    5g
    341.00€
    10g
    478.00€
    25g
    668.00€
    100g
    920.00€