CAS 113-59-7

Chlorprothixene

Description:

Chlorprothixene is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thioxanthene class of compounds and exhibits both antipsychotic and sedative properties. The chemical structure of chlorprothixene includes a thioxanthene core, which is characterized by a fused ring system containing sulfur and nitrogen atoms. This compound acts primarily as a dopamine antagonist, influencing neurotransmitter activity in the brain, particularly dopamine receptors, which is crucial for its therapeutic effects. Chlorprothixene is typically administered in oral form and may also be available as an injectable formulation. Its pharmacokinetics involve metabolism in the liver, with a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include sedation, weight gain, and extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its sedative effects, caution is advised when operating machinery or driving while on this medication. Overall, chlorprothixene is an important option in the pharmacological management of severe mental health conditions.

Formula: C₁₈H₁₈ClNS

InChI: InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7-

InChI key: InChIKey=WSPOMRSOLSGNFJ-AUWJEWJLSA-N

SMILES: C(\CCN(C)C)=C/1\C=2C(SC=3C1=CC=CC3)=CC=C(Cl)C2

Synonyms:

• (3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-aminium chloride
• (3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine
• (3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
• (Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine
• 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (3Z)-
• 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-
• 2-Chloro-3-(Dibenzo(B,E)Thiin-10-Ylidene)Propyldimethylamine
• 9H-Thioxanthene, 1-propanamine deriv.
• CPT
• CPX
• Chlorprothixen
• Chlorprotixen
• Chlorprotixene
• Chlothixen
• Chorprothixene
• Clorprotixeno
• Cloxan
• Iaractan
• Mk 184
• N 714
• Paxyl
• Rentovet
• Ro 4-0403
• Ro 4-04033
• Tactaran
• Taractan
• Tarasan
• Tardan
• Thioxanthene-Δ9,γ-propylamine, 2-chloro-N,N-dimethyl-, (Z)-
• Thioxanthene-Δ^9,γ-propylamine, 2-chloro-N,N-dimethyl-, (Z)-
• Traquilan
• Trictal
• Truxal
• Truxaletten
• Truxil
• Vetacalm
• cis-Chlorprothixene

Chlorprothixene

CAS: 113-59-7

Color and Shape: Neat

Ref: 61-FOR1321.09

{3-[(9Z)-2-chloro-9H-thioxanthen-9-ylidene]propyl}dimethylamine

CAS: 113-59-7

Formula: C₁₈H₁₈ClNS

Purity: 98%

Color and Shape: Solid

Molecular weight: 315.8602

Ref: IN-DA00785B

Chlorprothixene

CAS: 113-59-7

Chlorprothixene

Purity: ≥98%

Molecular weight: 315.86g/mol

Ref: 54-BUP17385

Chlorprothixene

CAS: 113-59-7

Chlorprothixene

Purity: 98%

Molecular weight: 315.86g/mol

Ref: 54-OR1029028

Chlorprothixene

CAS: 113-59-7

Formula: C₁₈H₁₈ClNS

Molecular weight: 315.86

Ref: 7W-GP9649

Chlorprothixene 100 µg/mL in Acetonitrile

CAS: 113-59-7

Formula: C₁₈H₁₈ClNS

Color and Shape: Single Solution

Molecular weight: 315.86

Ref: 04-A11503500AL-100

Chlorprothixene

CAS: 113-59-7

Formula: C₁₈H₁₈ClNS

Purity: >98.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 315.86

Ref: 3B-C3505

Chlorprothixene

CAS: 113-59-7

Chlorprothixene (Truxal) is a typical antipsychotic drug of the thioxanthene class, which was the first of the series to be synthesized.

Formula: C₁₈H₁₈ClNS

Purity: 98.77% - 99.756%

Color and Shape: Pale Yellow Crystals Solid

Molecular weight: 315.86

Ref: TM-T0074

Chlorprothixene

CAS: 113-59-7

Formula: C₁₈H₁₈ClNS

Molecular weight: 315.86

Ref: 4Z-C-335001

Chlorprothixene

CAS: 113-59-7

Applications Chlorprothixene
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package

Formula: C₁₈H₁₈ClNS

Color and Shape: White To Light Yellow

Molecular weight: 315.86

Ref: TR-C424910

Chlorprothixene

Controlled Product

CAS: 113-59-7

Chlorprothixene is a derivative of fluorescein and has been used in the treatment of bone cancer. The reaction mechanism of chlorprothixene is not well understood, but it is believed to be due to its ability to bind with 5-HT2 receptors. Chlorprothixene also has anti-inflammatory properties, which may be due to the inhibition of nitrogen atoms in immune cells. This drug has low potency and can cause drug interactions with other drugs that are metabolized by enzymes in the liver such as cytochrome P450 enzymes. It also has a trifluoroacetic acid substituent, which can cause significant pharmacokinetic changes when given intravenously.

Formula: C₁₈H₁₈ClNS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 315.86 g/mol

Ref: 3D-FC37587

Chlorprothixene

Controlled Product

CAS: 113-59-7

Formula: C₁₈H₁₈ClNS

Color and Shape: Neat

Molecular weight: 315.86

Ref: 04-C11503500