CAS 113-59-7: Chlorprothixene
Description:Chlorprothixene is an antipsychotic medication primarily used in the treatment of schizophrenia and other psychotic disorders. It belongs to the thioxanthene class of compounds and exhibits both antipsychotic and sedative properties. The chemical structure of chlorprothixene includes a thioxanthene core, which is characterized by a fused ring system containing sulfur and nitrogen atoms. This compound acts primarily as a dopamine antagonist, influencing neurotransmitter activity in the brain, particularly dopamine receptors, which is crucial for its therapeutic effects. Chlorprothixene is typically administered in oral form and may also be available as an injectable formulation. Its pharmacokinetics involve metabolism in the liver, with a relatively long half-life, allowing for once-daily dosing in many cases. Common side effects may include sedation, weight gain, and extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its sedative effects, caution is advised when operating machinery or driving while on this medication. Overall, chlorprothixene is an important option in the pharmacological management of severe mental health conditions.
Formula:C18H18ClNS
InChI:InChI=1S/C18H18ClNS/c1-20(2)11-5-7-14-15-6-3-4-8-17(15)21-18-10-9-13(19)12-16(14)18/h3-4,6-10,12H,5,11H2,1-2H3/b14-7-
InChI key:InChIKey=WSPOMRSOLSGNFJ-AUWJEWJLSA-N
SMILES:ClC1=CC=C2SC=3C=CC=CC3C(=CCCN(C)C)C2=C1
- Synonyms:
- (3E)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-aminium chloride
- (3Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine
- (3Z)-3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethylpropan-1-amine
- (Z)-3-(2-Chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-1-propanamine
- 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (3Z)-
- 1-Propanamine, 3-(2-chloro-9H-thioxanthen-9-ylidene)-N,N-dimethyl-, (Z)-
- 2-Chloro-3-(Dibenzo(B,E)Thiin-10-Ylidene)Propyldimethylamine
- 9H-Thioxanthene, 1-propanamine deriv.
- CPT
- CPX
- See more synonyms
- Chlorprothixen
- Chlorprotixen
- Chlorprotixene
- Chlothixen
- Chorprothixene
- Clorprotixeno
- Cloxan
- Iaractan
- Mk 184
- N 714
- Paxyl
- Rentovet
- Ro 4-0403
- Ro 4-04033
- Tactaran
- Taractan
- Tarasan
- Tardan
- Thioxanthene-Δ9,γ-propylamine, 2-chloro-N,N-dimethyl-, (Z)-
- Thioxanthene-Δ<sup>9,γ</sup>-propylamine, 2-chloro-N,N-dimethyl-, (Z)-
- Traquilan
- Trictal
- Truxal
- Truxaletten
- Truxil
- Vetacalm
- cis-Chlorprothixene
- α-Chlorprothixene