CAS 113-79-1: argipressin acetate
Description:Argipressin acetate, also known as vasopressin or antidiuretic hormone (ADH), is a peptide hormone that plays a crucial role in regulating water balance in the body. It is synthesized in the hypothalamus and stored in the posterior pituitary gland. The acetate form is a modified version that enhances its stability and bioavailability. This substance is characterized by its ability to promote water reabsorption in the kidneys, thereby concentrating urine and reducing water loss. Additionally, argipressin has vasoconstrictive properties, which can influence blood pressure. It is typically administered in clinical settings for conditions such as diabetes insipidus and certain types of shock. The molecular structure consists of a nonapeptide chain, and its activity is mediated through specific receptors in the kidneys and blood vessels. As a pharmaceutical agent, argipressin acetate is subject to strict regulatory controls, and its use must be carefully monitored to avoid potential side effects, including water retention and electrolyte imbalances.
Formula:C48H69N15O14S2
InChI:InChI=1/C46H65N15O12S2.C2H4O2/c47-27-22-74-75-23-33(45(73)61-17-5-9-34(61)44(72)56-28(8-4-16-53-46(51)52)39(67)54-21-37(50)65)60-43(71)32(20-36(49)64)59-40(68)29(14-15-35(48)63)55-41(69)31(18-24-6-2-1-3-7-24)58-42(70)30(57-38(27)66)19-25-10-12-26(62)13-11-25;1-2(3)4/h1-3,6-7,10-13,27-34,62H,4-5,8-9,14-23,47H2,(H2,48,63)(H2,49,64)(H2,50,65)(H,54,67)(H,55,69)(H,56,72)(H,57,66)(H,58,70)(H,59,68)(H,60,71)(H4,51,52,53);1H3,(H,3,4)/t27-,28-,29-,30-,31-,32-,33-,34-;/m0./s1
- Synonyms:
- Argipressine
- [8-Arginine]vasopressin
- 1,2-Dithia-5,8,11,14,17-pentaazacycloeicosane-10-propionamide, 19-amino-13-benzyl-7-(carbamoylmethyl)-4-[2-[[1-[(carbamoylmethyl)carbamoyl]-4-guanidinobutyl]carbamoyl]-1-pyrrolidinylcarbonyl]-16-p-hydroxybenzyl-6,9,12,15,18-pentaoxo-
- 3-(Phenylalanine)-8-arginineoxytocin
- 8-L-Arginine-vasopressin
- Arg8-vasopressin
- Arginine antidiuretic hormone
- Arginine-8-vasopressin
- Arginine-vasopressin
- Argipresina
- See more synonyms
- Argipressin
- AVP
- Glycinamide, L-cysteinyl-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-arginyl-, cyclic (1→6)-disulfide
- Leiormone
- Oxytocin, 3-(L-phenylalanine)-8-L-arginine-
- Pitressin
- Rindervasopressin
- Vasopressin, 8-L-arginine-