Rifamexil, with the CAS number 113102-19-5, is a synthetic antibiotic belonging to the rifamycin class, which is primarily used for its antibacterial properties. It is characterized by its ability to inhibit bacterial RNA synthesis by binding to the DNA-dependent RNA polymerase enzyme, making it effective against a range of Gram-positive and some Gram-negative bacteria. Rifamexil is particularly noted for its efficacy in treating infections caused by Mycobacterium tuberculosis and other mycobacterial species. The compound typically exhibits good oral bioavailability and is metabolized in the liver, with its pharmacokinetics influenced by various factors including dosage and patient-specific variables. As with other rifamycins, resistance can develop with prolonged use, necessitating careful management in therapeutic regimens. Additionally, it may interact with other medications due to its effects on liver enzymes, which can alter the metabolism of co-administered drugs. Overall, Rifamexil represents an important tool in the arsenal against bacterial infections, particularly in the context of tuberculosis treatment.

Rifamexil

113102-19-5: Rifamexil, with the CAS number 113102-19-5, is a synthetic antibiotic belonging to the rifamycin class, which is primarily used for its antibacterial properties. It is characterized by its ability to inhibit bacterial RNA synthesis by binding to the DNA-dependent RNA polymerase enzyme, making it effective against a range of Gram-positive and some Gram-negative bacteria. Rifamexil is particularly noted for its efficacy in treating infections caused by Mycobacterium tuberculosis and other mycobacterial species. The compound typically exhibits good oral bioavailability and is metabolized in the liver, with its pharmacokinetics influenced by various factors including dosage and patient-specific variables. As with other rifamycins, resistance can develop with prolonged use, necessitating careful management in therapeutic regimens. Additionally, it may interact with other medications due to its effects on liver enzymes, which can alter the metabolism of co-administered drugs. Overall, Rifamexil represents an important tool in the arsenal against bacterial infections, particularly in the context of tuberculosis treatment.

<p>Rifamexil is a rifamycin (antibiotic produced naturally by the bacterium Amycolatopsis rifamycinica) derivative.</p>

CAS 113102-19-5

Rifamexil

Rifamexil

Ref: TM-T26084