CAS 113108-86-4

9-(benzylamino)-1,2,3,4-tetrahydroacridin-1-ol (2Z)-but-2-enedioate (salt)

Description:

9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol (2Z)-but-2-enedioate (salt) is a chemical compound characterized by its complex structure, which includes a tetrahydroacridine core, a benzylamino group, and a butenedioate moiety. This compound is typically a salt form, indicating it may exhibit enhanced solubility and stability compared to its neutral counterpart. The presence of the benzylamino group suggests potential interactions with biological systems, making it of interest in medicinal chemistry. The tetrahydroacridine structure is often associated with various pharmacological activities, including neuroprotective effects. The butenedioate component may contribute to the compound's reactivity and solubility properties. Overall, this substance may exhibit unique characteristics such as specific melting and boiling points, solubility in various solvents, and potential biological activity, which can be explored further in research and development contexts. Its CAS number, 113108-86-4, serves as a unique identifier for regulatory and safety information.

Formula: C₂₄H₂₄N₂O₅

InChI: InChI=1/C20H20N2O.C4H4O4/c23-18-12-6-11-17-19(18)20(15-9-4-5-10-16(15)22-17)21-13-14-7-2-1-3-8-14;5-3(6)1-2-4(7)8/h1-5,7-10,18,23H,6,11-13H2,(H,21,22);1-2H,(H,5,6)(H,7,8)/b;2-1-

SMILES: c1ccc(cc1)CN=c1c2ccccc2[nH]c2CCCC(c12)O.C(=C\C(=O)O)\C(=O)O

Synonyms:

• (±)-9-(Benzylamino)-1,2,3,4-tetrahydro-1-acridinol maleate (1:1) (salt)
• 1,2,3,4-Tetrahydro-9-[(phenylmethyl)amino]-1-acridinol (±)-(Z)-2-butenedioate (1:1) (salt)
• 113108-86-4

9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol Maleate

Controlled Product

CAS: 113108-86-4

Stability Store in freezer at -20°C
Applications A potential Alzheimer's Disease therapeutic of low toxicity. Exhibits biochemical and pharmacological profile similar to THA except that it is far less toxic and without measurable liver toxicity in humans. Also showed potent in vitro inhibition of the uptake of radiolabeled noradrenaline and dopamine.
References Shutske, G.M., et al.: J. Med. Chem., 32, 1805 (1989)

Formula: C₂₀H₂₀N₂O·C₄H₄O₄

Color and Shape: Neat

Molecular weight: 420.46

Ref: TR-B230000

9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol maleate

CAS: 113108-86-4

9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol maleate is a cholinergic drug that is used for the treatment of inflammatory diseases. It inhibits phosphodiesterase activity and has been shown to be effective in clinical studies against a number of inflammatory diseases. This drug also has anti-inflammatory properties and can be used to treat acute inflammation. 9-(Benzylamino)-1,2,3,4-tetrahydroacridin-1-ol maleate is also conjugated with fatty acids and this formation helps to increase its bioavailability.

Formula: C₂₄H₂₄N₂O₅

Purity: Min. 95%

Molecular weight: 420.46 g/mol

Ref: 3D-FB18377