CAS 113158-34-2

Norbinaltorphimine dihydrochloride

CAS: 113158-34-2

Norbinaltorphimine dihydrochloride

Purity: ≥98%

Molecular weight: 734.71g/mol

Ref: 54-BUP21440

Norbinaltorphimine Dihydrochloride Salt-d6

Controlled Product

CAS: 113158-34-2

Formula: C₄₀H₃₉D₆Cl₂N₃O₆

Color and Shape: Neat

Molecular weight: 667.823

Ref: TR-N661127

Norbinaltorphimine Dihydrochloride Salt

Controlled Product

CAS: 113158-34-2

Applications Norbinaltorphimine Dihydrochloride Salt is a synthetic derivative of Naltrexone (N285750, HCl) and is useful as a κ-opioid antagonist.
References Agmo, A., et al.: Neuropharmacology, 37, 223 (1998); Nagase, H., et al.: Jpn. Kokai Tokkyo Koho. JP 03193782 A 19910823. Aug 23, 1991; Portoghese, P.S., et al.: J. Med. Chem., 31, 836 (1988)

Formula: C₄₀H₄₃N₃O₆·2ClH

Color and Shape: Neat

Molecular weight: 734.708

Ref: TR-N661125

Norbinaltorphimine dihydrochloride

Controlled Product

CAS: 113158-34-2

Norbinaltorphimine dihydrochloride is a potent, selective κ-opioid receptor agonist. It binds to the κ-opioid receptor on the cell surface and blocks the signal pathway that leads to the production of endothelin-a in cells. Norbinaltorphimine dihydrochloride has been shown to be effective for the treatment of oral pathogens such as Streptococcus pyogenes, Streptococcus pneumoniae, and Neisseria sp., as well as for prevention of myocardial infarction. Norbinaltorphimine dihydrochloride also has anti-inflammatory effects, which are mediated by its ability to inhibit prostaglandin synthesis through inhibition of cyclooxygenase activity.

Formula: C₄₀H₄₅Cl₂N₃O₆

Purity: Min. 95%

Molecular weight: 734.71 g/mol

Ref: 3D-NEA15834

Norbinaltorphimine dihydrochloride

CAS: 113158-34-2

Norbinaltorphimine dihydrochloride is a selective and potent κ opioid receptor antagonist that induces itch-associated responses in mice.

Formula: C₄₀H₄₅Cl₂N₃O₆

Purity: 98.17% - 99.88%

Color and Shape: Solid

Molecular weight: 734.71

Ref: TM-T12241