CAS 113215-69-3

N-acetyl-leucyl-phenylalanyl trifluoromethyl ketone

Description:

N-acetyl-leucyl-phenylalanyl trifluoromethyl ketone is a synthetic compound that belongs to the class of peptides and peptide derivatives. It features a trifluoromethyl ketone functional group, which is known for its reactivity and potential applications in medicinal chemistry. The presence of the N-acetyl group suggests that it may exhibit enhanced stability and bioavailability compared to its unmodified counterparts. This compound is often studied for its role as a protease inhibitor, particularly in the context of research related to enzyme activity and regulation. Its structure, comprising amino acid residues leucine and phenylalanine, indicates potential interactions with biological targets, making it of interest in drug design and development. The trifluoromethyl group can also influence the compound's lipophilicity and overall pharmacokinetic properties. As with many synthetic peptides, its solubility, stability, and biological activity can vary based on environmental conditions and the presence of other molecular entities.

Formula: C₁₈H₂₃F₃N₂O₃

InChI: InChI=1/C18H23F3N2O3/c1-11(2)9-15(22-12(3)24)17(26)23-14(16(25)18(19,20)21)10-13-7-5-4-6-8-13/h4-8,11,14-15H,9-10H2,1-3H3,(H,22,24)(H,23,26)/t14-,15-/m0/s1

SMILES: CC(C)C[C@@H](C(=N[C@@H](Cc1ccccc1)C(=O)C(F)(F)F)O)N=C(C)O

Synonyms:

• Ac-Leu-phe-CF3
• N-Acetyl-L-leucyl-L-phenylalanyltrifluoromethane
• Pentanamide, 2-(acetylamino)-4-methyl-N-(3,3,3-trifluoro-2-oxo-1-(phenylmethyl)propyl)-, (S-(R*,R*))-
• N~2~-acetyl-N-[(1S)-1-benzyl-3,3,3-trifluoro-2-oxopropyl]-L-leucinamide