CAS 1132749-48-4

N'-hydroxy-N-(2,3,4,5,6-pentadeuteriophenyl)octanediamide

Description:

N'-hydroxy-N-(2,3,4,5,6-pentadeuteriophenyl)octanediamide is a chemical compound characterized by its specific functional groups and isotopic labeling. The presence of the N-hydroxy group indicates that it can participate in hydrogen bonding, which may influence its solubility and reactivity. The pentadeuterated phenyl group suggests that the compound has been isotopically enriched with deuterium, which can be useful in studies involving nuclear magnetic resonance (NMR) spectroscopy or tracing mechanisms in chemical reactions. The octanediamide backbone indicates that the molecule contains two amine groups separated by an octane chain, which may impart certain hydrophobic characteristics while also allowing for potential interactions with biological systems. Overall, this compound's unique structure and isotopic composition make it a valuable tool in research, particularly in fields such as medicinal chemistry and biochemistry, where understanding molecular interactions and dynamics is crucial.

Formula: C₁₄H₁₅D₅N₂O₃

Synonyms:

• N'-hydroxy-N-(2,3,4,5,6-pentadeuteriophenyl)octanediamide
• [2H5]-Suberoylanilide Hydroxamic Acid

Suberoylanilide-d5 Hydroxamic Acid

Controlled Product

CAS: 1132749-48-4

Applications A potent, selective, cell permeable histone deacetylase inhibitor (HDAC). Displays anti-angiogenic activity by interfering with VEGF signaling in human umbilical vein endothelial cells (HUVECs). Induces differentiation in uman breast cancer cells.
References Richon, V.M., et al.: Proc. Natl. Acad.Sci. USA, 95, 3003 (1988), Munster, P.N., et al.: Cancer Res., 61, 8492 (2001), Deroanne, C.F., et al.: Oncogene, 21, 247 (2002),

Formula: C₁₄H₁₅D₅N₂O₃

Color and Shape: Neat

Molecular weight: 269.35

Ref: TR-S688702

Suberoylanilide-d5 hydroxamic acid

CAS: 1132749-48-4

Suberoylanilide-D5 hydroxamic acid is a high purity, stable, and potent activator of the N-type calcium channels. It has been shown to be a ligand for the nicotinic acetylcholine receptor (nAChR). Suberoylanilide-D5 hydroxamic acid is a cell permeable inhibitor of protein interactions with antibodies and peptides. It is an important research tool in Cell Biology, Pharmacology, Receptor Ligand Research, and Ion channels. Suberoylanilide-D5 Hydroxamic Acid can be used in the study of ion channel function.

Formula: C₁₄H₂₀N₂O₃

Purity: Min. 95%

Molecular weight: 269.35 g/mol

Ref: 3D-HVB74948