CAS 113294-82-9

angiopeptin

Description:

Angiopeptin, with the CAS number 113294-82-9, is a synthetic peptide that acts as a selective agonist for the somatostatin receptor subtype 2 (SSTR2). It is primarily known for its role in modulating various physiological processes, including inhibition of hormone secretion and regulation of cell proliferation. Angiopeptin exhibits a high affinity for SSTR2, which is significant in the context of cancer therapy and neuroendocrine tumors, as it can influence tumor growth and metastasis. The compound is characterized by its peptide structure, which typically includes a sequence of amino acids that confer its biological activity. Angiopeptin is often studied for its potential therapeutic applications, particularly in the fields of oncology and endocrinology, due to its ability to mimic the effects of natural somatostatin. Its pharmacological profile includes properties such as stability, bioavailability, and specificity, making it a subject of interest in drug development and research aimed at targeting somatostatin receptors for therapeutic benefits.

Formula: C₅₄H₇₁N₁₁O₁₀S₂

InChI: InChI=1/C54H71N11O10S2/c1-3-10-40(49(70)64-45(29-77)54(75)65-46(30(2)66)47(57)68)59-50(71)41(15-8-9-22-55)60-52(73)43(26-35-27-58-39-14-7-6-13-37(35)39)62-51(72)42(25-31-17-20-36(67)21-18-31)61-53(74)44(28-76)63-48(69)38(56)24-32-16-19-33-11-4-5-12-34(33)23-32/h4-7,11-14,16-21,23,27,30,38,40-46,58,66-67,76-77H,3,8-10,15,22,24-26,28-29,55-56H2,1-2H3,(H2,57,68)(H,59,71)(H,60,73)(H,61,74)(H,62,72)(H,63,69)(H,64,70)(H,65,75)/t30-,38-,40+,41+,42+,43-,44+,45+,46+/m1/s1

Synonyms:

• D-Nal-Cys-Tyr-Trp-Lys-Val-Cys-Thr-nh2
• 3-(2-Naphthyl)-D-Ala-Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-nh2
• (S)-6-amino-2-((R)-2-((S)-2-((R)-2-((R)-2-amino-3-(naphthalen-2-yl)propanamido)-3-mercaptopropanamido)-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N-((S)-1-(((R)-1-(((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide
• 3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide
• *Valproic Acid Impurity 76
• 3-(2-Naphthyl)alanyl-cystinyl-tyrosyl-tryptophyl-lysyl-valyl-cystinyl-threonine amide
• (S)-6-amino-2-((R)-2-((S)-2-((R)-2-((R)-2-amino-3-(naphthalen-2-yl)propanamido)-3-mercaptopropanamido)-3-(4-hydroxyphenyl)propanamido)-3-(1H-indol-3-yl)propanamido)-N-((S)-1-(((R)-1-(((2S,3R)-1-amino-3-hydroxy-1-oxobutan-2-yl)amino)-3-mercapto-1-oxopropan-2-yl)amino)-3-methyl-1-oxobutan-2-yl)hexanamide(WXG02269)
• L-Threoninamide, 3-(2-naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-
• Bim 23014 C
• 3-(naphthalen-2-yl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-norvalyl-L-cysteinyl-L-threoninamide
• Angiopeptin

Angiopeptin

CAS: 113294-82-9

Angiopeptin is a synthetic octapeptide analog of somatostatin; suppresses accelerated transplant atherosclerosis in rabbit heart arteries.

Formula: C₅₄H₇₁N₁₁O₁₀S₂

Color and Shape: Solid

Molecular weight: 1098.34

Ref: TM-T25087