CAS 1134163-31-7

5-[[4-[1,1,2,2-tetradeuterio-2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

Description:

The chemical substance known as 5-[[4-[1,1,2,2-tetradeuterio-2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione is a thiazolidinedione derivative, characterized by its thiazolidine ring structure, which contains a dione functional group. This compound features a complex molecular structure that includes a phenyl group substituted with an ethoxy group and a pyridine moiety, contributing to its potential biological activity. The presence of deuterium atoms indicates that it is a labeled compound, which can be useful in various analytical applications, including metabolic studies and tracing pathways in biological systems. Thiazolidinediones are known for their role in pharmacology, particularly in the treatment of diabetes, as they can enhance insulin sensitivity. The specific arrangement of substituents in this compound may influence its solubility, stability, and interaction with biological targets. Overall, this substance exemplifies the intricate design often found in medicinal chemistry, where modifications can lead to significant changes in biological activity and therapeutic potential.

Formula: C₁₉H₁₆D₄N₂O₃S

Synonyms:

• Pioglitazone-d4 (ethyl-d4)
• Phenyl Acetate Impurity 60
• 5-[[4-[1,1,2,2-tetradeuterio-2-(5-ethylpyridin-2-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione

Pioglitazone-d4 (major)

Controlled Product

CAS: 1134163-31-7

Applications Labelled Pioglitazone (P471000), which is used as an antidiabetic.A representative lot was 87% d4, 12% d3 no d0.
References Hofmann, C., et al.: Endocrinology, 129, 1915(1991), Kobayashi, M., et al.: Diabetes, 41, 476 (1992), Kawaamori, R., et al.,: Diabetes Res. Clin. Pract., 41, 35 (1998)

Formula: C₁₉H₁₆D₄N₂O₃S

Color and Shape: Off White

Molecular weight: 360.46

Ref: TR-P471002