CAS 1134822-07-3
:Kalydeco hydrate
Description:
Kalydeco hydrate, known scientifically as ivacaftor, is a medication primarily used in the treatment of cystic fibrosis in patients with specific mutations in the CFTR gene. It functions as a CFTR potentiator, enhancing the activity of the defective CFTR protein at the cell surface, thereby improving chloride transport and mucus clearance in the lungs. The substance is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, and oxygen atoms, and it typically appears as a white to off-white solid. Kalydeco hydrate is soluble in organic solvents and has a relatively low solubility in water, which can influence its bioavailability. The hydrate form indicates the presence of water molecules in its crystalline structure, which can affect its stability and solubility properties. As a pharmaceutical compound, it undergoes rigorous testing for efficacy and safety, and it is administered orally, often in combination with other therapies for optimal management of cystic fibrosis.
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Found 2 products.
Ivacaftor hydrate
CAS:<p>Ivacaftor is a small molecule that inhibits the CFTR protein. It is used as a research tool to study the function of CFTR and as an experimental treatment for cystic fibrosis. Ivacaftor is a potent, selective inhibitor of the CFTR protein with activity against all known mutations in the CFTR gene, including those that confer resistance to other drugs. Ivacaftor is not an agonist or antagonist, but instead blocks the channel by binding at its open state. The efficacy of ivacaftor was demonstrated in animal models and in clinical trials involving patients with cystic fibrosis who have specific mutations in their CFTR gene.<br>Ivacaftor has been shown to be effective in treating symptoms of cystic fibrosis such as pulmonary exacerbations, weight loss, and sweat chloride levels.</p>Formula:C24H30N2O4Purity:Min. 95%Molecular weight:410.5 g/molIvacaftor hydrate
CAS:<p>Ivacaftor hydrate is an orally bioavailable CFTR potentiator. It also is used for cystic fibrosis treatment.</p>Formula:C24H30N2O4Purity:98%Color and Shape:SolidMolecular weight:410.514
