CAS 1135318-57-8

ML-095 hydrochloride

CAS: 1135318-57-8

ML-095 hydrochloride

Purity: ≥98%

Molecular weight: 282.72g/mol

Ref: 54-BUP09791

ML-095 hydrochloride

CAS: 1135318-57-8

ML-095 hydrochloride (CID-25067483 hydrochloride) is a specific placental alkaline phosphatase inhibitor.

Formula: C₁₃H₁₅ClN₂O₃

Purity: 99.37%

Color and Shape: Solid

Molecular weight: 282.72

Ref: TM-T21969

ML095 hydrochloride

CAS: 1135318-57-8

ML095 hydrochloride is a phosphatase inhibitor that has shown anti-tumour activity in vitro and in vivo. It inhibits the enzyme placental alkaline phosphatase (PLAP) by binding to it, thereby preventing the removal of phosphate groups from substrates. This leads to an accumulation of substrate molecules, which may have an effect on cell signalling pathways and biological functions such as cell proliferation and migration. ML095 hydrochloride has been shown to modulate cancer cell growth in vitro and in vivo. This molecule also inhibits the activity of other phosphatases including pancreatic, testicular, and intestinal enzymes.
The compound is a potent inhibitor of bladder cancer cell growth in vitro and in vivo, as well as bladder carcinoma cells that express high levels of PLAP. The compound has been shown to be safe for use by children with cancer or those who have undergone surgery for bladder cancer at doses up to 10 mg/kg body weight.

Formula: C₁₃H₁₄N₂O₃·HCl

Purity: Min. 95%

Molecular weight: 282.72 g/mol

Ref: 3D-KVB31857