CAS 1135871-27-0

Tigecycline (Mesylate)

Description:

Tigecycline (mesylate) is a broad-spectrum antibiotic belonging to the glycylcycline class, derived from minocycline. It is primarily used to treat various bacterial infections, particularly those caused by multidrug-resistant organisms. Tigecycline exhibits a unique mechanism of action by inhibiting protein synthesis through binding to the 30S ribosomal subunit, which prevents the incorporation of amino acids into peptide chains. This antibiotic is effective against a range of Gram-positive and Gram-negative bacteria, including some strains of methicillin-resistant Staphylococcus aureus (MRSA) and Enterobacteriaceae. Tigecycline is typically administered intravenously and has a relatively long half-life, allowing for less frequent dosing. Its pharmacokinetics are characterized by extensive tissue distribution, although it has limited penetration into the central nervous system. Common side effects may include gastrointestinal disturbances, such as nausea and vomiting. Due to its broad activity and specific indications, tigecycline is often reserved for complicated infections where other antibiotics may be ineffective. However, its use is accompanied by considerations regarding potential resistance development and safety profiles.

Formula: C₃₀H₄₃N₅O₁₁S

Synonyms:

• Tigecycline (Mesylate)

Tigecycline mesylate

CAS: 1135871-27-0

Tigecycline mesylate is a first-in-class, broad-spectrum antibiotic. It also has activity against antibiotic-resistant organisms.

Formula: C₃₀H₄₃N₅O₁₁S

Purity: 98%

Color and Shape: Solid

Molecular weight: 681.75

Ref: TM-T23460

Tigecycline mesylate

CAS: 1135871-27-0

Tigecycline mesylate is a novel glycylcycline antibiotic, which is a derivative of the tetracycline class of antibiotics. It is a semi-synthetic product derived from minocycline, exhibiting a broad spectrum of antibacterial activity. Tigecycline mesylate functions through the inhibition of bacterial protein synthesis. It achieves this by binding to the 30S ribosomal subunit, thereby preventing the incorporation of amino acid residues into elongating peptide chains, a crucial step in protein production.

Formula: C₃₀H₄₃N₅O₁₁S

Purity: Min. 95%

Molecular weight: 681.8 g/mol

Ref: 3D-KVB87127