CAS 113603-74-0

O-demethylpaulomycin A

Description:

O-demethylpaulomycin A is a natural product derived from the fermentation of certain Streptomyces species, specifically known for its antibiotic properties. It belongs to the class of compounds known as polyketides, which are characterized by their complex structures and diverse biological activities. This compound exhibits significant antibacterial and antifungal activities, making it of interest in pharmaceutical research. O-demethylpaulomycin A is structurally related to other paulomycins, differing primarily in its demethylation at specific positions, which can influence its biological efficacy and mechanism of action. The compound's mechanism typically involves interference with protein synthesis in bacterial cells, contributing to its antimicrobial effects. Additionally, its potential applications in treating resistant bacterial infections are being explored, highlighting the importance of natural products in drug discovery. As with many bioactive compounds, further studies are necessary to fully understand its pharmacological properties, safety profile, and potential therapeutic uses.

Formula: C₃₃H₄₄N₂O₁₇S

Synonyms:

• 5-[6-(acetyloxymethyl)-4-[4,5-dihydroxy-6-methyl-5-[1-(2-methylbutanoyloxy)ethyl]oxan-2-yl]oxy-3-hydroxy-5-[(E)-2-isothiocyanatobut-2-enoyl]oxyoxan-2-yl]-2-amino-5-hydroxy-3,6-dioxocyclohexene-1-carboxylic acid
• O-demethylpaulomycin A
• O-Demethylpaulomycin
• 1-Cyclohexene-1-carboxylic acid, 5-[6-O-acetyl-3-O-[2,6-dideoxy-4-C-[[S-(S)]-1-(2-methyl-1-oxobutoxy)ethyl]-α-L-lyxo-hexopyranosyl]-4-O-[(Z)-2-isothiocyanato-1-oxo-2-buten-1-yl]-β-D-allopyranosyl]-2-amino-5-hydroxy-3,6-dioxo-, (S)-

O-Demethylpaulomycin A

CAS: 113603-74-0

O-Demethylpaulomycin A is an antibiotic known for its antibacterial properties. It is particularly effective against Gram-positive bacteria, including Staphylococcus aureus.

Formula: C₃₃H₄₄N₂O₁₇S

Color and Shape: Solid

Molecular weight: 772.771

Ref: TM-TN9996