CAS 113627-25-1

(2R,3S,11bS)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol

Description:

The chemical substance known as (2R,3S,11bS)-3-isobutyl-9,10-dimethoxy-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol, with the CAS number 113627-25-1, is a complex organic compound characterized by its multi-ring structure and specific stereochemistry. It features a benzoquinolizin framework, which is a bicyclic structure that incorporates nitrogen and exhibits a variety of functional groups, including methoxy and hydroxyl groups. The presence of isobutyl and methoxy substituents contributes to its unique chemical properties, potentially influencing its solubility, reactivity, and biological activity. The stereochemical configuration, indicated by the (2R,3S,11bS) notation, suggests that the compound has specific three-dimensional orientations that can affect its interaction with biological targets. Such compounds may be of interest in medicinal chemistry for their potential pharmacological effects, although detailed studies would be necessary to elucidate their biological activity and therapeutic applications.

Formula: C₁₉H₂₉NO₃

InChI: InChI=1/C19H29NO3/c1-12(2)7-14-11-20-6-5-13-8-18(22-3)19(23-4)9-15(13)16(20)10-17(14)21/h8-9,12,14,16-17,21H,5-7,10-11H2,1-4H3/t14-,16-,17+/m0/s1

cis-Dihydro Tetrabenazine

CAS: 113627-25-1

Formula: C₁₉H₂₉NO₃

Color and Shape: White To Off-White Solid

Molecular weight: 319.45

Ref: 4Z-T-784

β Hydroxy Tetrabenazine

CAS: 113627-25-1

Formula: C₁₉H₂₉NO₃

Molecular weight: 319.45

Ref: ST-EA-CP-T104002

cis (2,3)-Dihydro Tetrabenazine-d6

Controlled Product

CAS: 113627-25-1

Applications A labelled metabolite of Tetrabenazine in vivo, which is likely the active pharmacological agent. The cis izomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.
References Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995), Perera, R., et al.: J. Med. Chem., 46, 2599 (2003), Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005), Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006),

Formula: C₁₉H₂₃D₆NO₃

Color and Shape: Neat

Molecular weight: 325.48

Ref: TR-D449652

rac-(2,3)-Dihydro Tetrabenazine-13C2,D6 [Cis/Trans Mixture]

Controlled Product

CAS: 113627-25-1, 171598-74-6

Formula: C₁₇C₂H₂₃D₆NO₃

Color and Shape: Neat

Molecular weight: 654.922

Ref: TR-D450232

rac-(2,3)-Dihydro Tetrabenazine [Cis/Trans Mixture]

Controlled Product

CAS: 113627-25-1, 171598-74-6

Applications rac-(2,3)-Dihydro Tetrabenazine [Cis/Trans Mixture] is a mixture of cis-2,3-Dihydro Tetrabenazine (D449650) and trans-2,3-Dihydro Tetrabenazine (D449655); used in the treatment of hyperkinetic movement disorders.
References Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995); Perera, R., et al.: J. Med. Chem., 46, 2599 (2003); Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005); Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006)

Formula: C₁₉H₂₉NO₃

Color and Shape: Neat

Molecular weight: 638.877

Ref: TR-D450235

cis (2,3)-Dihydro Tetrabenazine

Controlled Product

CAS: 113627-25-1

Applications A metabolite of Tetrabenazine in vivo, which is likely the active pharmacological agent. The cis isomer of Dihydrotetrabenazine is used for the treatment of hyperkinetic movement disorders.
References Kilbourn, M., et al.: Eur. J. Pharmacol., 278, 249 (1995), Perera, R., et al.: J. Med. Chem., 46, 2599 (2003), Mager, D., et al.: J. Pharm. Sci., 94, 2475 (2005), Zheng, G., et al.: Bioorg. Med. Chem., 16, 5018 (2006),

Formula: C₁₉H₂₉NO₃

Color and Shape: Neat

Molecular weight: 319.44

Ref: TR-D449650