CAS 113658-85-8: Trombodipine

Description: Trombodipine is a chemical compound primarily recognized for its pharmacological properties, particularly as a vasodilator. It is classified as a selective inhibitor of phosphodiesterase type 5 (PDE5), which plays a crucial role in the regulation of blood flow and vascular tone. The compound is often studied for its potential therapeutic applications in conditions such as pulmonary hypertension and erectile dysfunction. Trombodipine exhibits a relatively high affinity for its target enzyme, leading to increased levels of cyclic guanosine monophosphate (cGMP) within vascular smooth muscle cells, resulting in relaxation and dilation of blood vessels. Its chemical structure includes specific functional groups that contribute to its biological activity and solubility characteristics. Additionally, the pharmacokinetics of Trombodipine, including its absorption, distribution, metabolism, and excretion, are essential for understanding its efficacy and safety profile in clinical settings. As with many pharmaceuticals, potential side effects and contraindications are important considerations in its therapeutic use.

Formula: C₂₁H₂₄N₂O₇S

InChI: InChI=1S/C21H24N2O7S/c1-5-29-20(25)17-12(2)18(14(4)22-13(17)3)21(26)30-11-10-23-19(24)15-8-6-7-9-16(15)31(23,27)28/h6-9,12,22H,5,10-11H2,1-4H3

InChI key: InChIKey=MCNAAGLIGWJLQX-UHFFFAOYSA-N

SMILES: O=C(OCC)C1=C(NC(=C(C(=O)OCCN2C(=O)C=3C=CC=CC3S2(=O)=O)C1C)C)C

Synonyms:

• 2-(1,1-dioxido-3-oxo-1,2-benzothiazol-2(3H)-yl)ethyl ethyl 2,4,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylate
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, 2-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ethyl ester
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, 3-[2-(1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl] 5-ethyl ester
• 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,4,6-trimethyl-, ethyl 2-(3-oxo-1,2-benzisothiazol-2(3H)-yl)ethyl ester, S,S-dioxide
• Pca-4230
• Trombodipine

Trombodipine

CAS: 113658-85-8

Trombodipine (PCA-4230) is a platelet aggregation inhibitor with antithrombotic activity and protection against Listeria monocytogenes.

• Formula: C₂₁H₂₄N₂O₇S
• Purity: 99.25% - 99.63%
• Color and Shape: Solid
• Molecular weight: 448.49

Trombodipine

CAS: 113658-85-8

Trombodipine is a platelet aggregation inhibitor and vasodilator that belongs to the class of fatty …

• Formula: C₂₁H₂₄N₂O₇S
• Purity: Min. 95%
• Molecular weight: 448.5 g/mol