CAS 113665-89-7
:(8Z)-5-O-Demethylavermectin A1a
Description:
(8Z)-5-O-Demethylavermectin A1a is a chemical compound belonging to the avermectin family, which are macrocyclic lactones produced by the fermentation of the bacterium Streptomyces avermitilis. This compound is characterized by its complex structure, which includes a macrocyclic lactone ring and multiple stereocenters, contributing to its biological activity. It exhibits potent insecticidal and antiparasitic properties, making it valuable in agricultural and veterinary applications. The compound functions primarily as a neurotoxin, affecting the nervous system of target organisms by enhancing the release of neurotransmitters, leading to paralysis and death. Its efficacy against a broad spectrum of pests and parasites has made it a key ingredient in various formulations. Additionally, (8Z)-5-O-Demethylavermectin A1a is subject to regulatory scrutiny due to its environmental impact and potential effects on non-target species. As with many avermectins, careful consideration of dosage and application methods is essential to minimize adverse effects while maximizing pest control efficacy.
Formula:C48H72O14
InChI:InChI=1/C48H72O14/c1-11-25(2)43-28(5)17-18-47(62-43)23-34-20-33(61-47)16-15-27(4)42(26(3)13-12-14-32-24-55-45-40(49)29(6)19-35(46(51)58-34)48(32,45)52)59-39-22-37(54-10)44(31(8)57-39)60-38-21-36(53-9)41(50)30(7)56-38/h12-15,17-19,25-26,28,30-31,33-45,49-50,52H,11,16,20-24H2,1-10H3/b13-12+,27-15+,32-14+/t25?,26-,28-,30?,31?,33+,34-,35?,36?,37?,38?,39?,40+,41?,42?,43+,44?,45+,47+,48+/m0/s1
InChI key:InChIKey=RRZXIRBKKLTSOM-XPNPUAGNSA-N
SMILES:O[C@]/12[C@@]3(OC\C1=C/C=C/[C@H](C)[C@H](O[C@]4(C[C@H](OC)[C@@H](O[C@]5(C[C@H](OC)[C@@H](O)[C@H](C)O5)[H])[C@H](C)O4)[H])\C(\C)=C\C[C@@]6(C[C@](OC(=O)[C@@]2(C=C(C)[C@H]3O)[H])(C[C@]7(O6)O[C@]([C@H](CC)C)([C@@H](C)C=C7)[H])[H])[H])[H]
Synonyms:- (8Z)-5-O-Demethylavermectin A1a
- Spiro[11,15-methano-2H,13H,17H-furo[4,3,2-pq][2,6]benzodioxacyclooctadecin-13,2′-[2H]pyran], avermectin A1a deriv.
- Avermectin A1a, 5-O-demethyl-, (8Z)-
- 8,9-Z-Abamectin B1a
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Found 4 products.
8,9-Z-Abamectin B1a
CAS:Controlled Product<p>Stability Light Sensitive<br>Applications 8,9-Z-Abamectin B1a is a photodegradation product of Avermectin B1a (A794665); a natural product derived from the soil actinomycete Streptomyces avermitilis. It is an antiparasitic agent that paralyzes nematodes without causing hypercontraction or flaccid paralysis.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Lofgren, C.S., et al.: J. Econ. Entomol., 75, 798 (1982); Kass, I.S., et al.: P. Natl. Acad. Sci. USA, 77, 6211 (1980); Fritz, L.C., et al.: P. Natl. Acad, Sci. USA, 76, 2062 (1979); Maynard, M.S., et al.: J. Agr. Food Chem., 37, 1487 (1989); Maynard, M.S., et al.: B. Environ. Contam. Tox., 43, 499 (1989); Crouch, L.S., et al.: J. Agr. Food Chem., 39, 1310 (1991)<br></p>Formula:C48H72O14Color and Shape:NeatMolecular weight:873.08
