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CAS 113712-08-6

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H-Arg-AMC . 2 HCl

Description:
H-Arg-AMC . 2 HCl, also known as H-Arginine-7-amido-4-methylcoumarin dihydrochloride, is a synthetic compound primarily used in biochemical research, particularly in studies involving proteases and enzyme activity. This substance features an arginine residue linked to a 7-amido-4-methylcoumarin (AMC) moiety, which serves as a fluorescent reporter group. The presence of two hydrochloride (HCl) molecules indicates that the compound is in a salt form, enhancing its solubility in aqueous solutions. H-Arg-AMC is characterized by its ability to release a fluorescent signal upon enzymatic cleavage, making it a valuable substrate for monitoring proteolytic activity in various biological assays. Its fluorescence properties allow for sensitive detection and quantification, facilitating studies in enzymology and cell biology. Additionally, the compound's stability and solubility in physiological conditions make it suitable for in vitro experiments. As with many biochemical reagents, proper handling and storage conditions are essential to maintain its integrity and functionality in experimental applications.
Formula:C16H23N5O3
InChI:InChI=1/C16H21N5O3/c1-9-7-14(22)24-13-8-10(4-5-11(9)13)21-15(23)12(17)3-2-6-20-16(18)19/h4-5,7-8,12H,2-3,6,17H2,1H3,(H,21,23)(H4,18,19,20)/p+2/t12-/m0/s1
Synonyms:
  • L-Arginine 7-amido-4-methylcoumarin dihydrochloride
  • (4S)-N~1~-(diaminomethylidene)-5-[(4-methyl-2-oxo-2H-chromen-7-yl)amino]-5-oxopentane-1,4-diaminium
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