CAS 113721-87-2: AMCA-NHS

Description: AMCA-NHS, or 7-Amino-4-methylcoumarin-3-acetic acid N-hydroxysuccinimide ester, is a fluorescent dye commonly used in bioconjugation and labeling applications. This compound features a coumarin moiety, which is known for its strong fluorescence properties, making it valuable in various biochemical assays and imaging techniques. The N-hydroxysuccinimide (NHS) ester functionality allows for efficient conjugation to amine-containing biomolecules, such as proteins and peptides, facilitating the formation of stable amide bonds. AMCA-NHS is typically characterized by its high solubility in polar solvents and its ability to emit fluorescence upon excitation, which is useful for detection and quantification in research settings. Additionally, the compound is sensitive to environmental factors such as pH and temperature, which can affect its stability and reactivity. Overall, AMCA-NHS is a versatile tool in molecular biology and biochemistry, enabling researchers to study protein interactions, localization, and dynamics through fluorescent labeling.

Formula: C₁₆H₁₄N₂O₆

InChI: InChI=1/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3

Synonyms:

• Succinimidyl-7-Amino-4-Methylcoumarin-3-Acetate
• N-Succinimidyl 7-Amino-4-Methyl-3-Coumarinylacetate
• Amca-Osu
• 7-Amino-4-Methyl-3-Coumarinacetic Acid N-Succinimidyl Ester
• 7-Amino-4-Methyl-3-Coumarinylacetyl
• 7-Amino-4-Methyl-3-Coumarinylacetyl Succinimidyl Ester
• 7-(Dimethylamino)coumarin-4-acetic acid-NHS
• 1-(benzyloxy)-2-methoxy-4-nitro-5-[(E)-2-nitroethenyl]benzene
• 1-{[(7-amino-4-methyl-2-oxo-2H-chromen-3-yl)acetyl]oxy}pyrrolidine-2,5-dione

2H-1-Benzopyran-3-acetic acid, 7-amino-4-methyl-2-oxo-, 2,5-dioxo-1-pyrrolidinyl ester

CAS: 113721-87-2

• Formula: C₁₆H₁₄N₂O₆
• Purity: 95%
• Color and Shape: Solid
• Molecular weight: 330.2922

AMCA-H N-succinimidyl ester

CAS: 113721-87-2

The amine-reactive AMCA, SE (7-amino-4-methylcoumarin-3-acetic acid, succinimidyl ester) and its conjugates yield blue-fluorescence (approximate excitation/

• Formula: C₁₆H₁₄N₂O₆
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 331.28

Succinimidyl-7-amino-4-methylcoumarin-3-acetate

CAS: 113721-87-2

• Color and Shape: Powder
• Molecular weight: 330.29g/mol

AMCA-H N-succinimidyl ester

CAS: 113721-87-2

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

CAS: 113721-87-2

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a synthetic amino acid with a reactive carboxylic acid group. …

• Formula: C₁₆H₁₄N₂O₆
• Purity: Min. 90 Area-%
• Color and Shape: Powder
• Molecular weight: 330.29 g/mol