CAS 113721-87-2

AMCA-NHS

Description:

AMCA-NHS, or 7-Amino-4-methylcoumarin-3-acetic acid N-hydroxysuccinimide ester, is a fluorescent dye commonly used in bioconjugation and labeling applications. This compound features a coumarin moiety, which is known for its strong fluorescence properties, making it valuable in various biochemical assays and imaging techniques. The N-hydroxysuccinimide (NHS) ester functionality allows for efficient conjugation to amine-containing biomolecules, such as proteins and peptides, facilitating the formation of stable amide bonds. AMCA-NHS is typically characterized by its high solubility in polar solvents and its ability to emit fluorescence upon excitation, which is useful for detection and quantification in research settings. Additionally, the compound is sensitive to environmental factors such as pH and temperature, which can affect its stability and reactivity. Overall, AMCA-NHS is a versatile tool in molecular biology and biochemistry, enabling researchers to study protein interactions, localization, and dynamics through fluorescent labeling.

Formula: C₁₆H₁₄N₂O₆

InChI: InChI=1/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3

SMILES: Cc1c2ccc(cc2oc(=O)c1CC(=O)ON1C(=O)CCC1=O)N

Synonyms:

• Succinimidyl-7-Amino-4-Methylcoumarin-3-Acetate
• N-Succinimidyl 7-Amino-4-Methyl-3-Coumarinylacetate
• Amca-Osu
• 7-Amino-4-Methyl-3-Coumarinacetic Acid N-Succinimidyl Ester
• 7-Amino-4-Methyl-3-Coumarinylacetyl
• 7-Amino-4-Methyl-3-Coumarinylacetyl Succinimidyl Ester
• 7-(Dimethylamino)coumarin-4-acetic acid-NHS
• 1-(benzyloxy)-2-methoxy-4-nitro-5-[(E)-2-nitroethenyl]benzene
• 1-{[(7-amino-4-methyl-2-oxo-2H-chromen-3-yl)acetyl]oxy}pyrrolidine-2,5-dione
• 7-(DiMethylaMino)couMarin-4-aceticcid-NHS
• AMCA-H N-succinimidyl ester
• AMCA-NHS
• 7-AMCA NHS ester
• (2,5-dioxopyrrolidin-1-yl) 2-(7-amino-4-methyl-2-o
• AMCA, SE [7-Amino-4-methyl-3-coumaricetic acid N-succinimidyl ester]
• AMCA-H NHS
• 2H-1-Benzopyran-3-acetic acid, 7-amino-4-methyl-2-oxo-, 2,5-dioxo-1-pyrrolidinyl ester
• AMCA, SE [7-AMino-4-Methyl-3-couMarinacetic acid N-succiniMidyl ester]
• AMCA NHS, 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

2H-1-BENZOPYRAN-3-ACETIC ACID, 7-AMINO-4-METHYL-2-OXO-, 2,5-DIOXO-1-PYRROLIDINYL ESTER

CAS: 113721-87-2

Formula: C₁₆H₁₄N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 330.2922

Ref: IN-DA0009GC

AMCA-H N-succinimidyl ester

CAS: 113721-87-2

The amine-reactive AMCA, SE (7-amino-4-methylcoumarin-3-acetic acid, succinimidyl ester) and its conjugates yield blue-fluorescence (approximate excitation/

Formula: C₁₆H₁₄N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 331.28

Ref: TM-TD0076

Succinimidyl-7-amino-4-methylcoumarin-3-acetate

CAS: 113721-87-2

Succinimidyl-7-amino-4-methylcoumarin-3-acetate

Purity: 95%

Color and Shape: Powder

Molecular weight: 330.29g/mol

Ref: 54-BIM107

AMCA-H N-succinimidyl ester

CAS: 113721-87-2

Ref: 7W-GW4752

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester

CAS: 113721-87-2

7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester is a synthetic amino acid with a reactive carboxylic acid group. It is used as a crosslinker in biochemistry and has been shown to have biological properties in plants. 7-Amino-4-methyl-3-coumarinacetic acid N-succinimidyl ester reacts with the acidic groups of proteins, DNA, or RNA, and is an important component of some second order rate constants. This chemical is also used for the neutralization of histological stains such as haematoxylin.

Formula: C₁₆H₁₄N₂O₆

Purity: Min. 90 Area-%

Color and Shape: Powder

Molecular weight: 330.29 g/mol

Ref: 3D-FA170610