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CAS 113721-87-2

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AMCA-NHS

Description:
AMCA-NHS, or 7-Amino-4-methylcoumarin-3-acetic acid N-hydroxysuccinimide ester, is a fluorescent dye commonly used in bioconjugation and labeling applications. This compound features a coumarin moiety, which is known for its strong fluorescence properties, making it valuable in various biochemical assays and imaging techniques. The N-hydroxysuccinimide (NHS) ester functionality allows for efficient conjugation to amine-containing biomolecules, such as proteins and peptides, facilitating the formation of stable amide bonds. AMCA-NHS is typically characterized by its high solubility in polar solvents and its ability to emit fluorescence upon excitation, which is useful for detection and quantification in research settings. Additionally, the compound is sensitive to environmental factors such as pH and temperature, which can affect its stability and reactivity. Overall, AMCA-NHS is a versatile tool in molecular biology and biochemistry, enabling researchers to study protein interactions, localization, and dynamics through fluorescent labeling.
Formula:C16H14N2O6
InChI:InChI=1/C16H14N2O6/c1-8-10-3-2-9(17)6-12(10)23-16(22)11(8)7-15(21)24-18-13(19)4-5-14(18)20/h2-3,6H,4-5,7,17H2,1H3
SMILES:Cc1c2ccc(cc2oc(=O)c1CC(=O)ON1C(=O)CCC1=O)N
Synonyms:
  • Succinimidyl-7-Amino-4-Methylcoumarin-3-Acetate
  • N-Succinimidyl 7-Amino-4-Methyl-3-Coumarinylacetate
  • Amca-Osu
  • 7-Amino-4-Methyl-3-Coumarinacetic Acid N-Succinimidyl Ester
  • 7-Amino-4-Methyl-3-Coumarinylacetyl
  • 7-Amino-4-Methyl-3-Coumarinylacetyl Succinimidyl Ester
  • 7-(Dimethylamino)coumarin-4-acetic acid-NHS
  • 1-(benzyloxy)-2-methoxy-4-nitro-5-[(E)-2-nitroethenyl]benzene
  • 1-{[(7-amino-4-methyl-2-oxo-2H-chromen-3-yl)acetyl]oxy}pyrrolidine-2,5-dione
  • 7-(DiMethylaMino)couMarin-4-aceticcid-NHS
  • See more synonyms
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