CAS 113743-17-2

2-[(6-hydroxypyridine-3-carbonyl)amino]ethyl nitrate

Description:

2-[(6-hydroxypyridine-3-carbonyl)amino]ethyl nitrate, with the CAS number 113743-17-2, is a chemical compound characterized by its unique functional groups and structural features. It contains a hydroxypyridine moiety, which contributes to its potential biological activity, and an amino group that links to an ethyl nitrate group. This structure suggests that the compound may exhibit both hydrophilic and lipophilic properties, influencing its solubility and reactivity. The presence of the nitrate group indicates potential for nitrate-related pharmacological effects, possibly involving vasodilation or other cardiovascular activities. Additionally, the hydroxypyridine component may impart chelating properties, allowing for interactions with metal ions. The compound's synthesis and stability can be influenced by environmental factors such as pH and temperature. Overall, 2-[(6-hydroxypyridine-3-carbonyl)amino]ethyl nitrate represents a complex molecule with potential applications in medicinal chemistry and pharmacology, warranting further investigation into its biological effects and mechanisms of action.

Formula: C₈H₉N₃O₅

InChI: InChI=1/C8H9N3O5/c12-7-2-1-6(5-10-7)8(13)9-3-4-16-11(14)15/h1-2,5H,3-4H2,(H,9,13)(H,10,12)

SMILES: c1cc(ncc1C(=NCCON(=O)=O)O)O

3-Pyridinecarboxamide, 1,6-dihydro-N-[2-(nitrooxy)ethyl]-6-oxo-

CAS: 113743-17-2

Formula: C₈H₉N₃O₅

Molecular weight: 227.1742

Ref: IN-DA0009JF

6-Hydroxy Nicorandil

CAS: 113743-17-2

Formula: C₈H₉N₃O₅

Color and Shape: White To Off-White Solid

Molecular weight: 227.18

Ref: 4Z-N-058

6-Hydroxy Nicorandil-d4

CAS: 113743-17-2

Formula: C₈H₅N₃O₅D₄

Molecular weight: 231.20

Ref: 4Z-N-059

6-Hydroxy Nicorandil

Controlled Product

CAS: 113743-17-2

Applications A metabolite of Nicorandil (N398500)
References Frydman, A., et al.: Am. J. Cardiol., 63, 25J (1989),

Formula: C₈H₉N₃O₅

Color and Shape: Neat

Molecular weight: 227.174

Ref: TR-H948550

6-Hydroxy Nicorandil-d4

Controlled Product

CAS: 113743-17-2

Applications 6-Hydroxy Nicorandil-d4 is the isotope labelled analog of 6-Hydroxy Nicorandil (H948550); a metabolite of the antianginal Nicorandil (N398500).
References Frydman, A., et al.: Am. J. Cardiol., 63, 25J (1989); Ma, C., et al.: J. Pharm. Biomed. Anal., 47, 677 (2008); Sudo, H., et al.: Biol. Pharm. Bull., 31, 2079 (2008); Iida, S., et al.: Brit. J. Clin. Pharmacol., 66, 352 (2008); Eguchi, Y., et al.: Ther. Res., 29, 316 (2008)

Formula: C₈D₄H₅N₃O₅

Color and Shape: Neat

Molecular weight: 231.199

Ref: TR-H948552

6-Hydroxy Nicorandil

CAS: 113743-17-2

Formula: C₈H₉N₃O₅

Molecular weight: 227.18

Ref: ST-EA-CP-N34005